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Reproductive Techniques for Ovarian Monitoring and Control in Amphibians
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Published on: May 12, 2019

Two pregnane oligoglycosides from Marsdenia roylei.

Versha Gupta1, Alok Kumar, Anakshi Khare

  • 1Department of Chemistry, Lucknow University, Lucknow 226007, India.

Natural Product Research
|September 8, 2009
PubMed
Summary

Two pregnane oligoglycosides, rocinine and marsdinine, were isolated from Marsdenia roylei. Their chemical structures were determined using advanced spectroscopic and chemical methods.

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Area of Science:

  • Natural Product Chemistry
  • Phytochemistry
  • Organic Chemistry

Background:

  • Marsdenia roylei is a plant species known for its potential medicinal properties.
  • Oligoglycosides are complex carbohydrates with significant biological activities.

Purpose of the Study:

  • To isolate and elucidate the structures of novel pregnane oligoglycosides from Marsdenia roylei.
  • To contribute to the understanding of the chemical constituents of this plant species.

Main Methods:

  • Isolation of compounds using chloroform soluble extract.
  • Structure elucidation employing Mass Spectrometry (MS).
  • Nuclear Magnetic Resonance (NMR) spectroscopy including (1)H NMR, (13)C NMR, (1)H-(1)H COSY, HSQC, and TOCSY.
  • Chemical degradation and derivatisation techniques.

Main Results:

  • Identification and structural characterization of two pregnane oligoglycosides: rocinine (1) and marsdinine (11).
  • Confirmation of their structures through comprehensive spectroscopic analysis and chemical transformations.

Conclusions:

  • The study successfully identified two new pregnane oligoglycosides from Marsdenia roylei.
  • The detailed structural information provides a basis for further pharmacological investigations.