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Related Concept Videos

Increased pulse rate01:17

Increased pulse rate

Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
Increased Body Temperature01:25

Increased Body Temperature

A body temperature above  38°C  (100.4 °F) is known as fever or pyrexia, and a person with fever is termed 'febrile.' Typically, the hypothalamus, a part of the brain that acts as the body's thermostat, regulates body temperature through a thermoregulatory setpoint. It receives signals from cold and warm thermal receptors throughout the body and adjusts the body's temperature accordingly. Fever occurs when this hypothalamic setpoint is altered, usually in response to an infection or illness.
Dysrhythmias III: Characteristics of Dysrhythmias01:29

Dysrhythmias III: Characteristics of Dysrhythmias

Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.
Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias01:25

ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias

Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
Methods of reducing fever01:22

Methods of reducing fever

The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:

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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management

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Ventricular tachycardia during hyperthermic intraperitoneal chemotherapy.

C A Thix1, I Königsrainer, R Kind

  • 1Department of Anaesthesiology and Critical Care Medicine, Tuebingen University Hospital, Tuebingen, Germany.

Anaesthesia
|September 9, 2009
PubMed
Summary

Cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC) can cause ventricular tachycardia. This arrhythmia may be linked to high cisplatin levels and low magnesium during HIPEC treatment for gastrointestinal cancers.

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Area of Science:

  • Oncology
  • Cardiology
  • Pharmacology

Background:

  • Cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy (HIPEC) is a standard treatment for specific gastrointestinal carcinomas.
  • HIPEC involves administering chemotherapy directly into the abdominal cavity at elevated temperatures.

Observation:

  • A case of ventricular tachycardia was observed during HIPEC treatment using cisplatin.
  • The ventricular tachycardia persisted as long as the cisplatin-containing chemotherapy solution remained within the abdominal cavity.

Findings:

  • The study hypothesizes that elevated plasma cisplatin levels, potentially exacerbated by low magnesium concentrations, were the cause of the observed ventricular tachycardia.
  • This suggests a direct correlation between cisplatin pharmacokinetics and cardiac electrical stability during HIPEC.

Implications:

  • This case highlights a potential cardiac complication associated with cisplatin-based HIPEC.
  • Further research is warranted to investigate the mechanisms linking cisplatin, magnesium levels, and cardiac arrhythmias in patients undergoing HIPEC.
  • Clinical monitoring for arrhythmias and electrolyte imbalances during HIPEC may be crucial for patient safety.