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Long-term clinical outcome after percutaneous coronary interventions in the elderly: results for 512 consecutive

N Boudou1, J Roncalli, T Lhermusier

  • 1Cardiology Department, Rangueil Hospital, Toulouse, France.

Eurointervention : Journal of Europcr in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
|September 9, 2009
PubMed

Insights

Elderly patients undergoing percutaneous coronary intervention (PCI) face similar short-term risks but increased long-term mortality. Co-morbidities, not age alone, significantly impact outcomes after PCI in older adults.

Area of Science:

  • Cardiology
  • Geriatric Medicine
  • Interventional Cardiology

Background:

  • Percutaneous coronary intervention (PCI) is increasingly used in elderly patients.
  • Limited data exists on the long-term outcomes of elective PCI in this demographic.
  • Defining risks for elderly patients undergoing contemporary PCI is crucial.

Purpose of the Study:

  • To evaluate the risks and long-term outcomes of elective percutaneous coronary intervention (PCI) in patients aged 75 years and older.
  • To identify predictors of in-hospital and long-term adverse events following PCI in the elderly population.

Main Methods:

  • Retrospective analysis of 512 consecutive patients aged over 75 undergoing PCI.
  • Comparison of outcomes between patients aged 75-79 and those over 80.
  • Assessment of in-hospital and long-term mortality and major adverse cardiovascular and cerebro-vascular events (MACCE).

Main Results:

  • No significant difference in in-hospital mortality or MACCE between age groups (75-79 vs. >80).
  • Independent predictors of in-hospital events included STEMI, LVEF <40%, and prior CABG.
  • Long-term mortality was significantly higher in the >80 group (42% vs. 26%), with predictors including LVEF <40%, creatinine rate, and prior carotid surgery/stroke.

Conclusions:

  • Age itself is not an independent predictor of morbidity or mortality after PCI.
  • Co-morbidities significantly influence long-term clinical outcomes in elderly patients undergoing PCI.
  • Risk stratification should consider factors beyond chronological age.
Abstract

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