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Related Experiment Video

Updated: Jun 20, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Imaging myocardial angiogenesis.

Joanna J Wykrzykowska1, Timothy D Henry, John R Lesser

  • 1The Thoraxcenter, Erasmus Medical Centre, Rotterdam, The Netherlands.

Nature Reviews. Cardiology
|September 9, 2009
PubMed
Summary
This summary is machine-generated.

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Advanced imaging techniques are crucial for visualizing myocardial angiogenesis, addressing limitations in current methods for ischemic heart disease research. New technologies promise improved resolution for clinical trials of angiogenic therapies.

Area of Science:

  • Cardiovascular Imaging
  • Molecular Imaging
  • Biomedical Engineering

Background:

  • Current clinical imaging methods like X-ray angiography and nuclear medicine lack the spatial resolution needed to accurately assess myocardial angiogenesis.
  • This resolution deficit limits the effectiveness of clinical trials evaluating novel angiogenic agents for ischemic heart disease.
  • Developing advanced imaging modalities is essential for progress in this field.

Purpose of the Study:

  • To review and examine cutting-edge techniques for imaging myocardial angiogenesis.
  • To highlight the potential of emerging technologies to overcome current resolution limitations.
  • To discuss the implications for scientific studies and clinical trials in ischemic heart disease.

Main Methods:

  • Exploration of specialized Magnetic Resonance Imaging (MRI), ultrasonography, echocardiography, and Computed Tomography (CT) techniques.

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Last Updated: Jun 20, 2026

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography
08:13

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography

Published on: February 16, 2016

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice
09:05

Minimal Invasive Surgical Procedure of Inducing Myocardial Infarction in Mice

Published on: May 4, 2015

  • Investigation of novel molecular imaging technologies designed to enhance resolution and provide mechanistic insights.
  • Review of current research and development in advanced imaging for angiogenesis.

    • Main Results:

    • Advanced MRI, ultrasonography, echocardiography, and CT show promise for improved myocardial angiogenesis imaging.
    • Molecular imaging technologies are under development to significantly boost resolution and mechanistic understanding.
    • These emerging technologies are expected to provide crucial data for scientific studies and clinical trials.

    Conclusions:

    • Advanced imaging methods, including specialized MRI, ultrasound, echocardiography, CT, and molecular imaging, are poised to revolutionize myocardial angiogenesis assessment.
    • These technologies offer the potential for higher resolution, enabling more effective evaluation of angiogenic therapies.
    • The successful implementation of these advanced techniques will significantly benefit research and clinical trials for ischemic heart disease.