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Updated: Jun 20, 2026

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents

Palatable Western-style Cafeteria Diet as a Reliable Method for Modeling Diet-induced Obesity in Rodents

Published on: November 1, 2019

Associations between dietary patterns and obesity phenotypes.

A-M Paradis¹, G Godin, L Pérusse

¹Department of Food Science and Nutrition, Laval University, Québec, Canada. marie-claude.vohl@crchul.ulaval.ca

International Journal of Obesity (2005)

|September 9, 2009

Summary

A Western dietary pattern is linked to increased obesity risk, while a Prudent pattern is associated with lower obesity risk, especially in individuals with a family history of obesity (FHO+).

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Fat Preference: A Novel Model of Eating Behavior in Rats

Fat Preference: A Novel Model of Eating Behavior in Rats

Published on: June 27, 2014

Area of Science:

Nutritional Science
Obesity Research
Public Health

Background:

Dietary patterns significantly influence health outcomes, including obesity.
Understanding the relationship between specific dietary patterns and obesity phenotypes is crucial for public health interventions.
The role of family history of obesity (FHO+) in moderating diet-obesity associations warrants investigation.

Purpose of the Study:

To investigate the association between distinct dietary patterns and obesity phenotypes.
To determine if these associations differ based on family history of obesity (FHO+).

Main Methods:

A cross-sectional study involving 664 participants aged 18-55 years.
Dietary patterns were identified using factor analysis of food frequency questionnaire data, revealing a 'Western' and a 'Prudent' pattern.
Obesity was defined by Body Mass Index (BMI) > or = 30 kg/m², with family history of obesity (FHO+) assessed.

Main Results:

The 'Western' dietary pattern, characterized by high consumption of refined grains and processed foods, was associated with higher BMI, weight, waist girth, and fat mass.
The 'Prudent' dietary pattern, rich in vegetables and fish, was linked to lower BMI, weight, waist girth, fat mass, and improved lipid profiles.
Individuals with high adherence to the 'Western' pattern were more likely to be obese (OR=1.82), while those with high adherence to the 'Prudent' pattern were less likely to be obese (OR=0.62). These associations were significant only in individuals with a positive family history of obesity (FHO+).

Conclusions:

Adherence to a 'Western' dietary pattern increases obesity risk, whereas a 'Prudent' pattern is protective against obesity.
These diet-obesity associations are particularly pronounced in individuals with a positive family history of obesity (FHO+).
Dietary interventions targeting specific patterns may be beneficial for obesity prevention, especially in genetically predisposed individuals.