Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vibratory perception threshold in diabetic neuropathy.

P H Tchen1, H C Chiu, C C Fu

  • 1Department of Neurology, College of Medicine, National Taiwan University, Taipei, R.O.C.

Journal of the Formosan Medical Association = Taiwan Yi Zhi
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Impact of donor characteristics on prognosis for myelodysplastic syndromes after haplo-identical transplantation: a retrospective study].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[Renal response and prognosis of newly diagnosed patients with multiple myeloma with renal impairment applying VRD and autologous hematopoietic stem cell transplantation].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[Development, reliability, and validity of a treatment-related quality of life scale for Chinese patients with multiple myeloma].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2025
Same author

[Interpretation of minimal residual disease for response evaluation in guidelines for the diagnosis and management of multiple myeloma in China (2024 revision)].

Zhonghua nei ke za zhi·2024
Same author

Influence of Obstructive Sleep Apnea on the Risk of Dental Caries: Insights from a 13-Year Population-Based Retrospective Study.

JDR clinical and translational research·2024
Same author

[Efficacy and safefy of Polymyxin B treatment for neutropenic patients suffering from refractory Gram-negative bacterial bloodstream infection].

Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi·2023
Same journal

Amplification refractory mutation system polymerase chain reaction-capillary electrophoresis's applicability for newborn screening in dried blood spots of spinal muscular atrophy.

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
Same journal

Comment on "Utilization of home-based traditional Chinese medicine in a homebound population under the integrated home-based medical care program in Taiwan".

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
Same journal

Further considerations on early energy delivery and metabolic patterns in indirect calorimetry-guided nutrition for surgical ICU patients.

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
Same journal

Response to "Comment on 'recent trends of LDL-C control and lipid-lowering therapy in patients with ASCVD in Taiwan: 2015-2020".

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
Same journal

Comment on "Satisfaction with bladder management in community-dwelling patients with chronic spinal cord injury".

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
Same journal

Comment on: SGLT2 inhibitors and geriatric syndromes in older adults with type 2 diabetes: A real-world cohort study.

Journal of the Formosan Medical Association = Taiwan yi zhi·2026
See all related articles

Diabetic neuropathy can be detected early using vibratory perception threshold (VPT) tests. Higher VPT values in diabetic patients indicate nerve damage, correlating with illness duration and severity.

Area of Science:

  • Neurology
  • Diabetology
  • Biomedical Engineering

Background:

  • Diabetic neuropathy is a common complication of diabetes mellitus.
  • Early detection of diabetic neuropathy is crucial for effective management and prevention of further complications.

Purpose of the Study:

  • To investigate the utility of vibratory perception threshold (VPT) as a sensitive indicator of diabetic neuropathy.
  • To correlate VPT measurements with clinical parameters of diabetes and nerve conduction studies.

Main Methods:

  • A study involving 263 diabetic patients and 129 healthy controls.
  • Vibratory perception threshold (VPT) measured using an electromagnetic vibrometer at the index finger (IF) and great toe (GT).
  • Nerve conduction velocity tests (motor and sensory) performed on 80 diabetic patients.

Related Experiment Videos

Main Results:

  • Diabetic patients exhibited significantly higher VPT values at both IF and GT compared to controls.
  • VPT values correlated with age (at GT), duration of illness, and diabetes severity.
  • A strong negative correlation was found between VPT and motor conduction velocity (MCV) in both upper and lower limbs.
  • VPT showed greater sensitivity than MCV in detecting neuropathic changes.

Conclusions:

  • Impaired vibratory perception is a subtle yet significant clinical sign of diabetic neuropathy.
  • VPT measurement serves as a valuable tool for assessing the subclinical neuropathic state in diabetic patients.
  • VPT testing offers a sensitive and accessible method for early detection of diabetic neuropathy.