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Published on: March 6, 2021
[Effects of high volume hemofiltration on postoperative multiple organ dysfunction syndrome in severe abdominal
Zhi-ge Yu1, Yi-lin Xu, Li-wei Zhu
1Department of General Surgery, General Hospital, Tianjin Medical University, Tianjin 300052, China.
Aim:
To evaluate the clinical efficacy of high-volume hemofiltration (HVHF) on treating postoperative multiple organ dysfunction syndrome in severe abdominal infection patients.
Methods:
Data of 17 severe abdominal infection patients treated with HVHF were collected and the differences on oxygenation indices, APACHE-II scores before and after HVHF therapy were observed.
Results:
After the first HVHF treatment, the oxygenation index improved, and the APACHE-II scores, TNF-alpha, IL-6, and IL-8 decreased significantly (P<0.05). After several HVHF treatments, the oxygenation index improved, and the APACHE-II scores decreased significantly (P<0.05).
Conclusion:
HVHF can improve both the respiratory function and vital signs of severe sepsis patients and relieve the severity of the illness.
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