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Updated: Jun 20, 2026

Venous Thrombosis Assay in a Mouse Model of Cancer
Published on: January 5, 2024
Catheter-associated thrombosis in patients with malignancy
Sudeep P Shivakumar1, David R Anderson, Stephen Couban
1Department of Medicine, Dalhousie University and Capital District Health Authority, Halifax, Nova Scotia, Canada.
Central venous catheters in cancer patients can cause upper extremity deep venous thrombosis. Early recognition and management are crucial for effective treatment and prevention in these individuals.
Area of Science:
- Oncology
- Vascular Medicine
- Medical Devices
Background:
- Central venous catheters are essential for cancer patient care.
- Catheter use is linked to upper extremity deep venous thrombosis (UEDVT).
- Recognizing UEDVT is vital for managing cancer patients.
Purpose of the Study:
- To review UEDVT associated with central venous catheters in cancer patients.
- To cover incidence, pathogenesis, presentation, diagnosis, treatment, and prophylaxis.
- To address pediatric cases of malignancy and catheter-associated thrombosis.
Main Methods:
- Literature review on catheter-associated thrombosis.
- Synthesis of data on incidence and risk factors.
- Compilation of diagnostic and treatment strategies.
Main Results:
- Central venous catheters are a significant risk factor for UEDVT in cancer patients.
- Early diagnosis and appropriate treatment improve patient outcomes.
- Prophylactic measures can reduce the incidence of thrombosis.
Conclusions:
- Catheter-associated thrombosis is a serious complication in cancer patients.
- Multidisciplinary management is key for effective care.
- Further research into prevention and treatment is warranted.
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