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Related Concept Videos

Accessory Structures of the Eye01:17

Accessory Structures of the Eye

Optical perception, or vision, is an extraordinary sense dependent on converting light signals received via the ocular organs. These organs, known as eyes, are securely positioned within the bony cavities of the skull, called orbits. The orbits serve a dual purpose: a protective shield for the ocular globes and a stable attachment point for the soft ocular tissues. The eye's external protective mechanisms include the eyelids, which are edged with lashes that act as a barrier against foreign...
Cranial Bones: Lateral View01:27

Cranial Bones: Lateral View

The lateral view of the cranium is dominated by temporal, sphenoid, and ethmoid bones.
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Circular Orbits and Critical Velocity for Satellites01:16

Circular Orbits and Critical Velocity for Satellites

The Moon orbits around the Earth. In turn, the Earth (and other planets) orbit the Sun. The space directly above our atmosphere is filled with artificial satellites in orbit. One can examine the circular orbit, the simplest kind of orbit, to understand the relationship between the speed and the period of planets and satellites with respect to their positions and the bodies that they orbit.
Nicolaus Copernicus (1473-1543) first suggested that the Earth and all other planets orbit the Sun in...
Cushing Syndrome II: Pathophysiology01:19

Cushing Syndrome II: Pathophysiology

Cortisol production is normally governed by the hypothalamic–pituitary–adrenal (HPA) axis, which maintains hormonal balance through tightly regulated feedback mechanisms. Disruption of this regulatory system is central to the development of Cushing syndrome, whether the excess cortisol originates from external medications or internal pathology. Persistent cortisol elevation alters metabolism, immune function, and endocrine signaling, producing the characteristic clinical features of the...

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Related Experiment Video

Updated: Jun 20, 2026

Three-Dimensional Reconstruction of Orbital Fractures
08:18

Three-Dimensional Reconstruction of Orbital Fractures

Published on: May 16, 2025

Orbital pseudotumor.

William M Mendenhall1, Alan M Lessner

  • 1Department of Radiation Oncology, University of Florida College of Medicine, 2000 SW Archer Road, Gainesville, FL 32610, USA. mendwm@shands.ufl.edu

American Journal of Clinical Oncology
|September 10, 2009
PubMed
Summary
This summary is machine-generated.

Orbital pseudotumor, a benign orbital mass, often responds to oral corticosteroids. Recurrent cases may require radiotherapy or chemotherapy for effective management.

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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

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Three-Dimensional Reconstruction of Orbital Fractures
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Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
04:48

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography

Published on: November 30, 2022

Area of Science:

  • Ophthalmology
  • Oncology

Background:

  • Orbital pseudotumor is a benign inflammatory condition representing about 10% of orbital masses.
  • It can affect any orbital structure, presenting acutely or subacutely with symptoms like pain, swelling, and vision changes.
  • Bilateral involvement occurs in approximately 25% of cases.

Purpose of the Study:

  • To review the clinical presentation, etiology, and management of orbital pseudotumor.
  • To outline treatment strategies, including first-line and second-line therapies.
  • To discuss prognosis and potential complications.

Main Methods:

  • Review of existing literature on orbital pseudotumor.
  • Analysis of clinical presentations and diagnostic indicators.
  • Evaluation of treatment outcomes for various therapeutic modalities.

Main Results:

  • Oral corticosteroids are effective initial treatment for about 80% of patients.
  • Relapse occurs in approximately 50% of responders, necessitating second-line treatments.
  • Second-line options include radiotherapy (50% local control), chemotherapy, and immunosuppressants.

Conclusions:

  • Orbital pseudotumor management requires a stepwise approach, starting with corticosteroids.
  • Radiotherapy and chemotherapy offer viable alternatives for refractory or relapsed cases.
  • While generally benign, severe cases may lead to vision loss and require extensive intervention.