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Related Experiment Video

Updated: Jun 20, 2026

Multimodality Diagnosis of Mesenteric Ischemia

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

Diffuse malignant peritoneal mesothelioma presenting as intestinal obstruction.

John Griniatsos¹, Stavros Sougioultzis, Nikoletta Dimitriou

¹Department of Surgery, University of Athens, Medical School, LAIKO Hospital, Athens, Greece. johngriniatsos@yahoo.com

Southern Medical Journal

|September 10, 2009

Summary

Diffuse malignant peritoneal mesothelioma (DMPM) can present atypically. Three patients without asbestos exposure or ascites developed bowel obstruction, highlighting a rare but critical DMPM presentation.

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Area of Science:

Oncology
Gastroenterology
Pathology

Background:

Diffuse malignant peritoneal mesothelioma (DMPM) is a rare cancer, typically associated with asbestos exposure and ascites.
It predominantly affects individuals aged 50-69, often presenting with nonspecific symptoms like abdominal pain and weight loss.

Observation:

This report details three DMPM cases in patients lacking asbestos exposure history and ascites.
These patients uniquely presented with complete bowel obstruction as their primary symptom.

Findings:

All three patients required emergency surgery for palliative procedures due to bowel obstruction.
The disease progression was rapid, with all patients succumbing to the illness within 3 to 6 months post-operation.

Implications:

These cases underscore the importance of considering DMPM in patients with unexplained bowel obstruction, even without typical risk factors.
Early diagnosis and management strategies for atypical DMPM presentations warrant further investigation to improve patient outcomes.