Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Strategies and governmental regulations.

A Carere1, R Benigni

  • 1Istituto Superiore di Sanità, Rome, Italy.

Teratogenesis, Carcinogenesis, and Mutagenesis
|January 1, 1990
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Evaluation of QSAR models for predicting mutagenicity: outcome of the Second Ames/QSAR international challenge project.

SAR and QSAR in environmental research·2023
Same author

Cervical lordosis after subaxial spinal trauma surgery: relationship with neck pain and stiffness.

Il Giornale di chirurgia·2020
Same author

Molecular fingerprint-derived similarity measures for toxicological read-across: Recommendations for optimal use.

Regulatory toxicology and pharmacology : RTP·2018
Same author

Deep spinal infection in instrumented spinal surgery: diagnostic factors and therapy.

Il Giornale di chirurgia·2017
Same author

Spontaneous chronic subdural hematoma in young adult: the role of missing coagulation facto.

Il Giornale di chirurgia·2017
Same author

Understanding genetic toxicity through data mining: the process of building knowledge by integrating multiple genetic toxicity databases.

Toxicology mechanisms and methods·2009

This study reviews genotoxin detection strategies using OECD Guidelines and EEC Directive 79/831. It discusses key aspects of genetic toxicology, including test roles and mutagen classification.

Area of Science:

  • Toxicology
  • Genetics
  • Regulatory Science

Background:

  • Genotoxins pose risks requiring standardized detection methods.
  • Regulatory frameworks like OECD Guidelines and EEC Directive 79/831 guide genotoxicity testing.
  • The Italian National Advisory Committee on Toxicology provides expert perspectives.

Purpose of the Study:

  • To provide an overview of genotoxin detection testing strategies.
  • To present the viewpoint of the Italian National Advisory Committee on Toxicology.
  • To discuss central issues in genetic toxicology.

Main Methods:

  • Review of existing testing strategies for genotoxin detection.
  • Analysis of guidelines from the Organisation for Economic Co-operation and Development (OECD).

Related Experiment Videos

  • Examination of the European Economic Community (EEC) Directive 79/831 (VI Amendment).

    • Main Results:

    • Outlined testing strategies for genotoxin detection under international guidelines.
    • Presented the Italian National Advisory Committee on Toxicology's perspective.
    • Discussed the role of various tests in genetic toxicology.
    • Addressed the classification of mutagens based on test outcomes.

    Conclusions:

    • Standardized testing strategies are crucial for genotoxin detection.
    • Genetic toxicology plays a vital role in risk assessment.
    • Further discussion on test selection and mutagen classification is warranted.