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Updated: Jun 20, 2026

Combining Chemical Cross-linking and Mass Spectrometry of Intact Protein Complexes to Study the Architecture of Multi-subunit Protein Assemblies
Published on: November 28, 2017
massXpert 2: a cross-platform software environment for polymer chemistry modelling and simulation/analysis of mass
1Laboratoire de Biophysique, Muséum National d'Histoire Naturelle, CNRS UMR7196-INSERM U565-MNHN USM0503, Paris, France. rusconi@mnhn.fr
Unlabelled:
Since the middle of the 90s, mass spectrometry has evolved into an almost indispensable tool in structural studies on an ever-growing variety of (bio-)polymers, of which proteins, sugars and nucleic acids are the most prominent. Since the first public release of massXpert, the advances of mass spectrometry have motivated continuous and thorough maintenance of that software, in the form of two full software rewrites, culminating with massXpert 2, which we describe in this report. We shall describe the profound changes in massXpert that were performed so as to keep up with the technical advances in mass spectrometry since a decade.
Availability:
The massXpert 2 software is an open source and free software project hosted at http://www.massxpert.org.
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