Related Experiment Video
Updated: Jun 20, 2026

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
Published on: April 28, 2019
Acute disseminated encephalomyelitis-like manifestations in a patient with neuro-Behçet disease
Afshin Borhani Haghighi1, Nahid Ashjazadeh
1Department of Neurology, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. borhanihaghighi@yahoo.com
Objective:
To describe a patient with a rare presentation of neuro-Behçet disease.
Methods And Results:
A 42-year-old patient with definite Behçet disease was referred to Nemazee Hospital, affiliated to Shiraz University of Medical Sciences, Shiraz, South of Iran, with headache, biparesis, left central facial palsy, and urinary dysfunction. Brain magnetic resonance imaging revealed a hypo/hypersignal lesion in T1-/T2-weighted images in the right cerebral peduncle extending to the right basal ganglia. Cervical magnetic resonance imaging showed a lesion in the parenchyma of the spinal cord extending from C2 to T1 which was iso-hyperintense in T1-/T2-weighted images. Initial cerebrospinal fluid analysis revealed significant pleocytosis, hypoglycorrhachia and increased protein content. The patient had an incomplete response to treatment with corticosteroids and cyclophosphamide.
Conclusions:
An acute disseminated encephalomyelitis (ADEM)-like presentation is a rare manifestation of neuro-Behçet disease.
Related Concept Videos
Encephalitis l: Introduction
Encephalitis ll: Pathophysiology
Arboviral Encephalitis
Multiple Sclerosis l: Introduction
Bacterial Meningitis
Hepatic Encephalopathy

