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Antihistaminic activity of pulegone on the guinea-pig ileum
A V Ortiz de Urbina1, M L Martin, M J Montero
1Department of Physiology and Pharmacology, Faculty of Pharmacy, University of Salamanca, Spain.
The Journal of Pharmacy and Pharmacology
|April 1, 1990
Abstract:
Pulegone, a natural monoterpene compound, has an antihistamine effect on guinea-pig ileum. Its antagonism is of the competitive type (PA2 = 6.35) like that of mepyramine and dexchlorpheniramine, two H1-antagonists, with PA2 values of 10.15 and 8.74, respectively.