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Related Concept Videos

Candidiasis01:20

Candidiasis

Candidiasis is a fungal infection caused by opportunistic species of Candida. It can affect various anatomical sites, including the skin, oral cavity, nails, and genitourinary tract. Among its forms, vaginal candidiasis is the most common type of mucosal infection. It typically results from the overgrowth of Candida albicans in the vaginal mucosa. Under normal conditions, C. albicans exists as a commensal organism within the vaginal microbiota, regulated by the dominance of lactobacilli, which...
Protein Networks02:26

Protein Networks

An organism can have thousands of different proteins, and these proteins must cooperate to ensure the health of an organism. Proteins bind to other proteins and form complexes to carry out their functions. Many proteins interact with multiple other proteins creating a complex network of protein interactions.
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...

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Related Experiment Video

Updated: Jun 20, 2026

An Optimized Protocol for Candida albicans Infection in Schmidtea mediterranea to Study Fungal Pathogenesis and Host Defense
06:53

An Optimized Protocol for Candida albicans Infection in Schmidtea mediterranea to Study Fungal Pathogenesis and Host Defense

Published on: April 17, 2026

Proteopathogen, a protein database for studying Candida albicans--host interaction.

Vital Vialás1, Rubén Nogales-Cadenas, César Nombela

  • 1Departamento de Microbiología II, Facultad de Farmacia, Universidad Complutense de Madrid, Madrid, Spain.

Proteomics
|September 11, 2009
PubMed
Summary

Proteopathogen is a new database for fungal pathogen proteomics data. It facilitates storage and access to experimental details, focusing initially on Candida albicans interactions with host cells.

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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

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Last Updated: Jun 20, 2026

An Optimized Protocol for Candida albicans Infection in Schmidtea mediterranea to Study Fungal Pathogenesis and Host Defense
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An Optimized Protocol for Candida albicans Infection in Schmidtea mediterranea to Study Fungal Pathogenesis and Host Defense

Published on: April 17, 2026

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Genome-wide Profiling of Transcription Factor-DNA Binding Interactions in Candida albicans: A Comprehensive CUT&RUN Method and Data Analysis Workflow

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A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions
13:56

A Comparative Approach to Characterize the Landscape of Host-Pathogen Protein-Protein Interactions

Published on: July 18, 2013

Area of Science:

  • Fungal Pathogen Research
  • Proteomics
  • Bioinformatics

Background:

  • Existing public repositories lack focus on fungal pathogen proteomics.
  • There is a need for specialized databases integrating experimental workflows and host-pathogen interaction data.

Purpose of the Study:

  • To introduce Proteopathogen, a novel database for fungal pathogen proteomics.
  • To provide a centralized resource for storing and accessing comprehensive proteomics data related to fungal pathogens and host interactions.

Main Methods:

  • Compilation of proteomics experimental data.
  • Inclusion of details on experimental approaches, sample preparation, and mass spectrometry settings.
  • Data organization to support protein identification via peptide evidence.

Main Results:

  • Proteopathogen is established as a dedicated repository.
  • The database currently focuses on *Candida albicans* interactions with macrophages.
  • It is designed to accommodate data from diverse fungal species and host cells.

Conclusions:

  • Proteopathogen addresses a critical gap in fungal pathogen research resources.
  • It offers a valuable platform for researchers studying fungal proteomics and host interactions.
  • The database promotes data sharing and accessibility in the field.