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Related Concept Videos

Phase II Reactions: Methylation Reactions01:17

Phase II Reactions: Methylation Reactions

Methylation is a phase II biotransformation process involving the attachment of a methyl group to a substrate. Enzymes known as methyltransferases orchestrate this reaction.
The mechanism of methylation unfolds in two stages. The first stage sees a methyltransferase enzyme facilitating the transfer of a methyl group from S-adenosylmethionine (SAM) to the substrate, forming S-adenosylhomocysteine (SAH). The second stage involves further metabolism of SAH into homocysteine, which can be recycled...
Olefin Metathesis Polymerization: Overview01:13

Olefin Metathesis Polymerization: Overview

Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization.
Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...
Microbes and Methanogenesis01:26

Microbes and Methanogenesis

Methanogenesis is a critical microbial process in anaerobic ecosystems responsible for the biological production of methane, a potent greenhouse gas and valuable biofuel. This metabolic pathway is primarily facilitated by methanogenic archaea, which thrive in anoxic environments such as wetlands, sediments, and animal gastrointestinal tracts. The absence of oxygen in these habitats prevents aerobic respiration, thereby favoring alternative biochemical pathways for organic matter degradation.In...
Carboxylic Acids to Methylesters: Alkylation using Diazomethane01:33

Carboxylic Acids to Methylesters: Alkylation using Diazomethane

Carboxylic acids react with diazomethane in an ether solvent via alkylation at the carboxylate oxygen atom to give methyl esters of the corresponding acid with excellent yields.
Mass Spectrum01:23

Mass Spectrum

A mass spectrum is the graphical representation of the relative abundance of the charged fragments in an analyte plotted against their mass-to-charge ratio (m/z). The plot's x-axis represents the ratio of the mass of the charged fragment to the number of charges it carries. The y axis of the plot represents the relative abundance of each charged species. The relative abundance is calculated from the signal intensity of each charged species recorded at the detector. The most intense signal (the...
¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)01:20

¹³C NMR: Distortionless Enhancement by Polarization Transfer (DEPT)

When proton-coupled carbon-13 spectra are simplified by a broadband proton decoupling technique, structural information about the coupled protons is lost. Distortionless enhancement by polarization transfer (DEPT) is a technique that provides information on the number of hydrogens attached to each carbon in a molecule. While the DEPT experiment utilizes complex pulse sequences, the pulse delay and flip angle are specifically manipulated. The resulting signals have different phases depending on...

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Related Experiment Video

Updated: Jun 20, 2026

A Mass Spectrometry-Based Proteomics Approach for Global and High-Confidence Protein R-Methylation Analysis
09:40

A Mass Spectrometry-Based Proteomics Approach for Global and High-Confidence Protein R-Methylation Analysis

Published on: April 28, 2022

Meth mout.

Christine K Heng1, Victor M Badner, Luminita Adela Schiop

  • 1cheng@bop.gov

Hawaii Dental Journal
|September 12, 2009
PubMed
Summary
This summary is machine-generated.

Methamphetamine (meth) use has surged into the mainstream, leading to increased dental problems like "meth mouth." This condition involves rampant tooth decay, requiring specific dental treatment considerations.

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Last Updated: Jun 20, 2026

A Mass Spectrometry-Based Proteomics Approach for Global and High-Confidence Protein R-Methylation Analysis
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Multi-step Preparation Technique to Recover Multiple Metabolite Compound Classes for In-depth and Informative Metabolomic Analysis
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Multi-step Preparation Technique to Recover Multiple Metabolite Compound Classes for In-depth and Informative Metabolomic Analysis

Published on: July 11, 2014

Area of Science:

  • Public Health
  • Dentistry
  • Addiction Medicine

Background:

  • Methamphetamine (meth) use has transitioned from fringe groups to the mainstream.
  • Recent years show a significant increase in meth abuse, media attention, and law enforcement focus.
  • Methamphetamine abuse is associated with severe oral health issues, commonly termed 'meth mouth'.

Purpose of the Study:

  • To provide a historical overview of methamphetamine use and abuse.
  • To describe the clinical characteristics and causes of meth mouth.
  • To discuss treatment strategies and dental management for individuals with meth mouth.

Main Methods:

  • Literature review on methamphetamine history and effects.
  • Clinical description of meth mouth pathology.
  • Analysis of current treatment modalities for meth-related dental conditions.

Main Results:

  • Methamphetamine abuse is linked to a specific pattern of rampant dental caries.
  • The etiology of meth mouth involves drug-induced xerostomia, bruxism, and poor oral hygiene.
  • Effective management requires a multi-faceted approach addressing addiction and dental restoration.

Conclusions:

  • Methamphetamine abuse presents a growing public health and dental challenge.
  • Early intervention and comprehensive dental care are crucial for managing meth mouth.
  • Understanding the history and etiology of meth use informs treatment and prevention strategies.