Sequence analysis of the S10 gene of six Bluetongue Virus isolates from India

Bluetongue Virus (BTV) genome segment 10 (S10)-based phylogenetic studies are important in understanding the BTV evolution. S10 gene-based phylogenetic analysis grouped six different BTV isolates (BTV serotype 1, 18 and 23) from India in subclade A1 and showed closer relationship with BT viruses from Mediterranean Basin. Indian BTV serotypes 18 and 23 formed a single cluster distinct from BTV serotype 1 isolates and were evolved from BTV from China, Indonesia and Australia. The overall S10 sequences of BTV isolates from India were largely conserved (>95.7% homology) and were distinct from other BT viruses of the world.