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Updated: Jun 20, 2026

A Murine Model of Hyperlipidemia-Induced Heart Failure with Preserved Ejection Fraction
Published on: March 29, 2024
[The hyperlipidemia diagnosis based on phenotype]
Olga Aude-Rueda1, Gloria Aguilar-Nungaray, Antonio Villa-Romero
1Facultad de Medicina, Universidad Autónoma de Veracruz Villa Rica, Boca del Río, Veracruz, Mexico.
Objective:
to describe the different clinical profiles of patients with dyslipidemia based on lipid phenotype, in an urban setting.
Methods:
a survey was carried out among college students and general population. A structured interview was conducted. Blood was drawn for glucose and lipid profile from subjects considered to be healthy.
Results:
we included 1286 subjects. They were grouped by socioeconomic status (low income = 437, medium income = 162 and high income = 133) and 554 college students who had lived in the area for at least one year. Women composed 61 % of the cohort; 86 % of the cases were studied after an overnight fasting period. The prevalent lipid phenotype was hypoalphalipoproteinemia, followed by mixed hyperlipidemia. Among medium income group, isolated hypercholesterolemia was a common finding. High fasting glucose and low c-HDL were observed among the low income group. Male gender and age are predictors for hypercholesterolemia. The BMI is the only identified predictor of hypertriglyceridemia (OR = 10.089). We identified that age > 55-year old (OR = 2.6), male gender (OR = 1.6), and sedentary life (OR = 1.35), were predictors of hypoalphalipoproteinemia.
Conclusion:
the most common lipid phenotype was hypoalphalipoproteinemia.
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