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Related Concept Videos

Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
Spinal Nerves: Plexus II01:21

Spinal Nerves: Plexus II

The plexuses of the lower body include the lumbar, sacral, and coccygeal plexuses, which innervate the abdomen, pelvis, legs, and coccygeal region. These plexuses control the transmission of sensory information and coordinate motor functions of the lower body.
The Lumbar Plexus
The lumbar plexus is situated within the lumbar region of the back and is primarily formed by the first four lumbar spinal nerves (L1 to L4). This plexus extends its branches into several nerves, including the...
Nerve Supply of the GI Tract01:27

Nerve Supply of the GI Tract

The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of the GI tract...

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Related Experiment Video

Updated: Jun 20, 2026

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
03:59

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy

Published on: January 10, 2019

Coeliac plexus neurolysis.

Ian D Penman1

  • 1Western General Hospital, Edinburgh, UK. ian.penman@luht.scot.nhs.uk

Best Practice & Research. Clinical Gastroenterology
|September 12, 2009
PubMed
Summary
This summary is machine-generated.

Endoscopic ultrasound-guided coeliac plexus neurolysis (EUS-CPN) offers a precise method for managing pancreatic pain. This technique targets coeliac ganglia directly, potentially enhancing treatment efficacy for chronic pain conditions.

Related Experiment Videos

Last Updated: Jun 20, 2026

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy
03:59

Targeting Gray Rami Communicantes in Selective Chemical Lumbar Sympathectomy

Published on: January 10, 2019

Area of Science:

  • Gastroenterology
  • Pain Management
  • Interventional Endoscopy

Background:

  • Coeliac plexus neurolysis (CPN) is a long-standing treatment for pancreatic cancer pain.
  • Endoscopic ultrasound (EUS)-guided CPN is increasingly preferred, but evidence supporting its superiority is limited.
  • Direct injection into coeliac ganglia via EUS may improve CPN efficacy.

Purpose of the Study:

  • To describe the technique of EUS-guided CPN.
  • To review the evidence supporting the use of EUS-CPN.
  • To discuss recent advancements in EUS-CPN procedures.

Main Methods:

  • Review of existing literature on CPN and EUS-guided interventions.
  • Description of the technical aspects of performing EUS-CPN.
  • Analysis of studies comparing EUS-CPN with other neurolysis methods.

Main Results:

  • EUS-guided CPN allows for precise targeting of the coeliac ganglia.
  • Studies suggest potential for improved pain relief and reduced complications with EUS-CPN.
  • Direct injection techniques show promise for enhanced therapeutic outcomes.

Conclusions:

  • EUS-CPN is an evolving technique for pancreatic pain management.
  • Further research is needed to solidify the superiority of EUS-CPN over traditional methods.
  • Advancements in EUS-guided injections represent a significant step in optimizing CPN.