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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice
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Characterizing Salmonella Typhimurium-induced Septic Peritonitis in Mice

Published on: July 29, 2022

Typhoid fever in Ethiopia.

Getenet Beyene1, Daniel Asrat, Yohannes Mengistu

  • 1Department of Medical Microbiology, Immunology and Parasitology, Addis Ababa University, Addis Ababa, Ethiopia. rgetenet@yahoo.com

Journal of Infection in Developing Countries
|September 12, 2009
PubMed
Summary

Typhoid fever remains a significant public health issue in Ethiopia, with increasing drug resistance and a rise in non-Typhi Salmonella infections. More research is needed to assess the true burden of enteric fever.

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Published on: September 22, 2019

Area of Science:

  • Microbiology
  • Epidemiology
  • Public Health

Background:

  • Salmonellosis, particularly typhoid fever, is a persistent health concern in Ethiopia.
  • Limited online accessibility of local research hinders comprehensive understanding of disease trends.
  • Existing studies indicate ongoing challenges with typhoid fever up to 2000.

Purpose of the Study:

  • To review and synthesize available reports on salmonellosis and typhoid fever in Ethiopia.
  • To highlight the prevalence of typhoid fever and antimicrobial resistance patterns.
  • To identify gaps in surveillance and research capacity.

Main Methods:

  • Literature review of published and local reports on salmonellosis in Ethiopia.
  • Analysis of studies diagnosing typhoid fever via laboratory culture.
  • Examination of trends in reported cases and serovar prevalence.

Main Results:

  • Typhoid fever was common in Ethiopia until at least 2000, with significant multiple drug resistance observed.
  • A decline in published typhoid fever cases may reflect reduced research capacity.
  • Non-Typhi Salmonella serovars appear to be increasing in proportion.

Conclusions:

  • Typhoid fever is a current public health problem in Ethiopia.
  • There is an urgent need for population-based surveys with robust microbiological diagnosis.
  • Effective public health interventions, including vaccination, require accurate disease burden estimation.