Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Caged Garcinia xanthones: development since 1937.

Quan-Bin Han1, Hong-Xi Xu

  • 1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, Yunnan, China.

Current Medicinal Chemistry
|September 15, 2009
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

Fruit Development, Structure, and Function01:58

Fruit Development, Structure, and Function

24.8K
Fruits form from a mature flower ovary. As seeds develop from the ovules contained within, the ovary wall undergoes a series of complex changes to form fruit. In some fruits, such as soybeans, the ovary wall dries; in other fruits, such as grapes, it remains fleshy. In some cases, organs other than the ovary contribute to fruit formation; such fruits are called accessory fruits.
24.8K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Protective effects of Prunella vulgaris polysaccharides against herpes simplex virus type 1 infection through the STING-TBK1-IRF3 pathway.

Journal of integrative medicine·2026
Same author

Potential of phytochemicals in the treatment of Alzheimer disease by modulating lysosomal dysfunction: a systematic review.

Chinese medicine·2025
Same author

Therapeutic role of Prunella vulgaris L. polysaccharides in non-alcoholic steatohepatitis and gut dysbiosis.

Journal of integrative medicine·2025
Same author

Author Correction: Ginsenoside Rg1 mitigates cerebral ischaemia/reperfusion injury in mice by inhibiting autophagy through activation of mTOR signalling.

Acta pharmacologica Sinica·2025
Same author

Anti-inflammatory bicyclic polyprenylated acylphloroglucinols with diverse architectures including an unprecedented 6/6/6 tricyclic core from Garcinia yunnanensis.

Bioorganic chemistry·2024
Same author

20(S)-Ginsenoside Rh2 overcomes gemcitabine resistance in pancreatic cancer by inhibiting LAMC2-Modulated ABC transporters.

Journal of advanced research·2024
Same journal

Screening of Medicinal and Edible Homology Substances for Diabetic Kidney Disease Based on GraphBAN.

Current medicinal chemistry·2026
Same journal

Berberine as an Antimicrobial Agent and Gut Microbiota Modulator: Mechanisms and Therapeutic Potential.

Current medicinal chemistry·2026
Same journal

Research Progress of Grapefruit-derived Extracellular Vesicles in Anti-tumor Treatment.

Current medicinal chemistry·2026
Same journal

Corrigendum to: Neuroprotective Mechanisms of Oxygen and Ethanol: A Potential Combination Therapy in Stroke.

Current medicinal chemistry·2026
Same journal

Ferroptosis and Its Crosstalk with Other Cell Death Modes in Ischemic Stroke.

Current medicinal chemistry·2026
Same journal

Integrative Analysis Reveals BPTF, COL1A1, and COL4A2 as Fibroblast-Related Biomarkers Associated with Immune Infiltration in Ovarian Cancer.

Current medicinal chemistry·2026
See all related articles

Caged xanthones from the Garcinia genus exhibit potent antitumor activity. This review details their structure, synthesis, and potential as anticancer drugs.

Area of Science:

  • Natural Product Chemistry
  • Medicinal Chemistry
  • Organic Chemistry

Background:

  • Caged xanthones are a unique class of bioactive compounds primarily found in the Garcinia genus.
  • These compounds feature a distinctive 4-oxa-tricyclo[4.3.1.0(3,7)]dec-2-one scaffold.
  • Over 100 caged xanthones have been identified, with many demonstrating significant antitumor properties.

Observation:

  • Gambogic acid is a prominent example of a caged xanthone with potent anticancer effects.
  • The unusual skeletal structure and potent bioactivity of caged xanthones have spurred scientific interest.
  • Research spans various fields, including natural product chemistry, synthetic chemistry, and pharmacology.

Findings:

  • This review comprehensively covers plant resources, structural elucidation, and total synthesis of caged xanthones.

Related Experiment Videos

  • It details their diverse biological activities, mechanisms of action, and structure-activity relationships (SAR).
  • The development of caged xanthones as potential anticancer drugs is a key focus.

    • Implications:

    • Caged xanthones represent a promising scaffold for the development of novel anticancer therapeutics.
    • Understanding their SAR can guide the design of more effective and selective antitumor agents.
    • Further research into caged xanthones could lead to new strategies in cancer drug discovery.