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Related Experiment Video

Updated: Jun 20, 2026

Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors

Standard Membrane Feeding Assay for the Detection of Plasmodium falciparum Infection in Anopheles Mosquito Vectors

Published on: May 12, 2022

Malaria zoonoses.

J Kevin Baird¹

¹Eijkman-Oxford Clinical Research Unit, Jalan Diponegoro No. 69, Jakarta 10430, Indonesia. kbaird@eocru.org

Travel Medicine and Infectious Disease

|September 15, 2009

Summary

This summary is machine-generated.

Zoonotic malaria, caused by Plasmodium knowlesi from non-human primates, poses a significant risk to humans, especially in Southeast Asia. This review examines the biology and medical implications of this emerging infectious disease.

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Area of Science:

Primates and infectious diseases
Parasitology
Public health

Background:

The genus Plasmodium comprises species that infect primates, causing malaria.
The discovery of Plasmodium knowlesi infections in humans in 2004 highlighted the zoonotic potential of simian malaria.
Plasmodium knowlesi poses a significant risk for severe disease and mortality in humans, particularly in Southeast Asia.

Purpose of the Study:

To review the biology and medicine of Plasmodium knowlesi zoonosis.
To examine the spectrum of Plasmodium species that can infect humans.
To raise awareness of the public health implications of simian malaria in humans.

Main Methods:

Literature review of Plasmodium knowlesi biology and clinical cases.
Analysis of epidemiological data on human Plasmodium infections.
Examination of Plasmodium species with zoonotic potential.

Main Results:

Plasmodium knowlesi is a significant cause of human malaria in Southeast Asia.
Infections can lead to severe disease and mortality, even in travelers.
Other Plasmodium species may also pose a zoonotic risk.

Conclusions:

Plasmodium knowlesi represents a critical emerging zoonotic threat.
Enhanced surveillance and diagnostic capabilities are needed for simian malaria in humans.
Understanding the biology of Plasmodium species is crucial for preventing and treating human infections.