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Related Concept Videos

Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Unsymmetric Bending01:18

Unsymmetric Bending

Unsymmetrical bending occurs when the bending moment applied to a structural member does not align with its principal axis. This misalignment leads to complex stress distributions and deflection patterns that differ from those in symmetrical bending, and are essential for designing structures to withstand different loading conditions. In unsymmetrical bending, the neutral axis—where stress is zero—does not necessarily align with the geometric axes of the cross-section. The orientation of the...
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Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Chirality in Nature02:30

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Chirality is the most intriguing yet essential facet of nature, governing life’s biochemical processes and precision. It can be observed from a snail shell pattern in a macroscopic world to an amino acid, the minutest building block of life. Most of the snails around the world have right-coiled shells because of the intrinsic chirality in their genes. All the amino acids present in the human body exist in an enantiomerically pure state, except for glycine - the sole achiral amino acid. The...
Yellow Fever01:18

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Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Unsymmetric Bending - Angle of Neutral Axis01:15

Unsymmetric Bending - Angle of Neutral Axis

Unsymmetrical bending occurs when a structural member is subjected to bending moments in a plane that does not align with the member's principal axes. This scenario typically arises in beams and other structural components when loads are applied at non-ideal angles, introducing complexities in stress analysis.
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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1

Published on: March 13, 2018

Chikungunya: a bending reality.

Zhisheng Her1, Yiu-Wing Kam, Raymond T P Lin

  • 1Singapore Immunology Network, Agency for Science, Technology and Research, Immunos, Singapore.

Microbes and Infection
|September 15, 2009
PubMed
Summary
This summary is machine-generated.

Chikungunya fever, an arboviral illness, re-emerged globally in 2005. This review covers its history, transmission by Aedes mosquitoes, clinical features, and control, impacting arboviral disease management.

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Multiplexed Isothermal Amplification Based Diagnostic Platform to Detect Zika, Chikungunya, and Dengue 1
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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
10:35

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Area of Science:

  • Arbovirology
  • Epidemiology
  • Public Health

Background:

  • Chikungunya fever is an acute illness caused by the Chikungunya virus, an arbovirus transmitted by Aedes mosquitoes.
  • A significant outbreak began in 2005, leading to global spread via travelers.
  • The disease causes fever, rash, and severe, long-lasting joint pain.

Purpose of the Study:

  • To review the history and characteristics of Chikungunya fever.
  • To detail the virus, its host specificity, and clinical manifestations.
  • To discuss current control strategies and the impact on arboviral disease management.

Main Methods:

  • Literature review of Chikungunya fever history, virology, and epidemiology.
  • Analysis of clinical features and disease spectrum.
  • Summary of existing control measures and public health implications.

Main Results:

  • The Chikungunya virus re-emerged significantly in 2005, causing widespread outbreaks.
  • The virus exhibits a sylvatic cycle and is transmitted by Aedes mosquitoes.
  • Clinical presentation includes fever, rash, and debilitating arthralgia.

Conclusions:

  • The re-emergence of Chikungunya virus has reshaped the management of arboviral diseases.
  • Understanding its history, transmission, and clinical impact is crucial for public health.
  • Effective control measures are essential to mitigate the global burden of Chikungunya fever.