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Safety and durability of mitral valve repair for anterior leaflet perforation

Basar Sareyyupoglu1, Hartzell V Schaff, Rakesh M Suri

  • 1Division of Cardiovascular Surgery, Mayo Clinic, Rochester, MN 55905, USA.

The Journal of Thoracic and Cardiovascular Surgery
|September 15, 2009
PubMed
Abstract

Insights

Mitral valve anterior leaflet perforation can be safely repaired, offering good midterm survival and durability. This surgical repair effectively addresses severe mitral regurgitation and improves left ventricular dimensions.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Valve Repair
  • Thoracic Surgery

Background:

  • Anterior leaflet perforation of the mitral valve is a rare but serious condition.
  • This condition often leads to severe mitral regurgitation and requires surgical intervention.

Purpose of the Study:

  • To evaluate the safety and efficacy of mitral valve repair specifically for anterior leaflet perforation.
  • To assess the midterm survival and durability of this repair technique.

Main Methods:

  • A retrospective review of 26 patients who underwent mitral valve repair for anterior leaflet perforation between 1987 and 2006.
  • Analysis of surgical techniques, including patch repair versus primary suture closure, and concomitant procedures.
  • Evaluation of postoperative outcomes, including survival rates, left ventricular dimensions, and reoperation rates.

Main Results:

  • The majority of patients (92%) had endocarditis; 50% had preoperative aortic regurgitation.
  • Mitral valve repair demonstrated high survival rates: 95% at 1 year and 90% at 5 years.
  • Significant improvement in left ventricular end-diastolic dimension was observed post-repair, with only one reoperation due to recurrent endocarditis.

Conclusions:

  • Mitral valve anterior leaflet perforation can be safely and effectively repaired.
  • The repair offers good midterm survival and durability, with significant functional improvement.

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