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Updated: Jun 20, 2026

An Optimized Hemagglutination Inhibition (HI) Assay to Quantify Influenza-specific Antibody Titers
Published on: December 1, 2017
Influenza vaccination in healthcare workers
Hasan Naz1, Figen Cevik, Nevil Aykin
1Department of Infectious Diseases, Eskisehir Yunus Emre State Hospital, Eskisehir, Turkey. hasannaz73@mynet.com
Background:
This study aims to determine side effects in healthcare workers receiving influenza vaccination, and to scrutinize the opinion of and attitude toward vaccination of healthcare workers.
Methods:
Five hundred forty-seven hospital personnel employed by the Eskişehir Yunus Emre State Hospital were included in the study which was conducted in November 2006,. Hospital personnel were administered 0.5 ml inactivated influenza vaccine consisting of 2006/2007 strains. Inoculations were given intramuscularly into the deltoid muscle. A specially designated area in the emergency unit was used for the procedure.
Results:
An evaluation on Day 10 following influenza vaccination demonstrated at least one adverse effect in 197 (36%) hospital personnel. There was no statistical relationship between side effects and age or gender (p=0.860, p=0.929), while side effects were significantly more frequent among subjects receiving their first vaccination (p=0.008) and nurses (p=0.021). The reasons for the lack of prior immunization in 420 (76.8%) HCWs included not considering influenza a serious disease in 124 (29.5%), disbelief in the efficacy of vaccination in 109 (26%), the lack of reimbursement of vaccination in 105 (25%), fear of the side effects of vaccination in 45 (10.7%), preference for other methods of protection in 75 (17.9%), and fear of injection in 29 (6.9%).
Conclusions:
The increase in the rate of influenza immunization among healthcare personnel is possible through education, contestation of fear, amelioration of misconceptions, solution of financial issues, constitution of a registry system, and tracking of vaccination.
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