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MICROBIOME AND UVEITIDES. A REVIEW.

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IMMUNE-MEDIATED INTRAOCULAR INFLAMMATION. A REVIEW.

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Updated: Jun 20, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

[Malignant masquerade syndromes].

J Heissigerová1, E Ríhová, P Svozílková

  • 1Centrum pro diagnostiku a lécbu uveitid, Ocní klinika VFN a 1. LF UK, Praha. j.heissigerova@yahoo.co.uk

Ceska a Slovenska Oftalmologie : Casopis Ceske Oftalmologicke Spolecnosti a Slovenske Oftalmologicke Spolecnosti
|September 16, 2009
PubMed
Summary
This summary is machine-generated.

Malignant masquerade syndromes, often misdiagnosed as idiopathic uveitis, require prompt diagnosis. Analysis of intraocular fluids is key for identifying these serious conditions and improving patient outcomes.

Related Experiment Videos

Last Updated: Jun 20, 2026

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models
08:57

Identifying, Diagnosing, and Grading Malignant Peripheral Nerve Sheath Tumors in Genetically Engineered Mouse Models

Published on: May 17, 2024

Area of Science:

  • Ophthalmology
  • Oncology
  • Immunology

Context:

  • Masquerade syndromes present a diagnostic challenge in ophthalmology, mimicking chronic uveitis.
  • Intraocular tumors and lymphomas can present as masquerade syndromes, necessitating careful evaluation.
  • Idiopathic uveitis is a common initial diagnosis for masquerade syndromes, delaying appropriate treatment.

Purpose:

  • To evaluate the diagnostic and treatment experience with malignant masquerade syndromes.
  • To identify the most frequent causes and effective diagnostic methods for malignant masquerade syndromes.

Summary:

  • A retrospective study analyzed 46 patients with malignant masquerade syndromes, a subset of 89 masquerade syndromes identified from 1233 uveitis cases.
  • Intraocular non-Hodgkin lymphoma was the most common cause (26 patients).
  • Analysis of intraocular fluids proved to be the most valuable diagnostic procedure.

Impact:

  • Highlights the importance of considering malignant masquerade syndromes in corticosteroid-resistant chronic uveitis.
  • Emphasizes that timely diagnosis and treatment can improve prognosis and potentially control life-threatening conditions.