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Published on: December 11, 2017
Long-term survival of the very elderly undergoing aortic valve surgery
Donald S Likosky1, Meredith J Sorensen, Lawrence J Dacey
1Department of Surgery, Dartmouth-Hitchcock Medical Center, Hanover, NH, USA. donald.likosky@dartmouth.edu
Insights
Survivorship after aortic valve replacement (AVR) and AVR with coronary artery bypass graft (CABG) surgery is favorable for octogenarians. More than half of patients over 80 survive over 6 years, with CABG not negatively impacting survival.
Area of Science:
- Cardiology
- Geriatric Surgery
- Outcomes Research
Background:
- An increasing number of elderly individuals are undergoing aortic valve procedures.
- This study focuses on the short- and long-term survival rates within this specific patient demographic.
Purpose of the Study:
- To evaluate the survivorship of very elderly patients undergoing aortic valve surgery.
- To compare outcomes between isolated aortic valve replacement (AVR) and AVR with concomitant coronary artery bypass graft (CABG) surgery in patients aged 80 and older.
Main Methods:
- A cohort study included 7584 patients undergoing open aortic valve surgery between 1987 and 2006.
- Patient records were analyzed and linked to the Social Security Administration's Death Master File for survivorship data.
- Survivorship was stratified by age groups (<80, 80-84, >=85 years) and procedure type (AVR vs. AVR + CABG).
Main Results:
- Over 39,835 person-years of follow-up, 2877 deaths occurred.
- Median survivorship for isolated AVR was 11.5 years (<80), 6.8 years (80-84), and 6.2 years (>=85).
- Median survivorship for AVR + CABG was 9.4 years (<80), 6.8 years (80-84), and 7.1 years (>=85), with age significantly impacting survival (P<0.001).
Conclusions:
- Survivorship among octogenarians undergoing aortic valve procedures is favorable, with over half surviving more than 6 years.
- Concomitant CABG surgery does not appear to diminish median survivorship in patients over 80 years of age.
- The findings suggest that advanced age alone should not be a contraindication for these procedures.
Background:
Increasing numbers of the very elderly are undergoing aortic valve procedures. We describe the short- and long-term survivorship for this cohort.
Methods And Results:
We conducted a cohort study of 7584 consecutive patients undergoing open aortic valve surgery without (51.1%; AVR) or with (48.9%; AVR + CABG) concomitant coronary artery bypass graft surgery between November 10, 1987 through June 30, 2006. Patient records were linked to the Social Security Administration's Death Master File. Survivorship was stratified by age and concomitant CABG surgery. During 39 835 person-years of follow-up, there were 2877 deaths. Among AVR, there were 3304 patients <80 years of age, 419 patients 80 to 84 years, and 156 patients > or =85 years (24 patients >90 years). Among AVR+CABG patients, there were 2890 patients <80 years of age, 577 patients 80 to 84 years, and 238 patients > or =85 years (22 patients >90 years). Median survivorship for patients undergoing isolated AVR was 11.5 years (<80 years), 6.8 years (80 to 84 years), 6.2 years (> or =85 years); for patients undergoing AVR+CABG, median survivorship was 9.4 years (<80 years), 6.8 years (80 to 84 years), and 7.1 years (> or =85 years). Among both procedures, adjusted survivorship was significantly different across strata of age (P<0.001). These findings are similar to life expectancy of the general population from actuarial tables: 80 to 84 years (7 years) and > or =85 years (5 years).
Conclusions:
Survivorship among octogenarians is favorable, with more than half the patients surviving more than 6 years after their surgery. Concomitant CABG surgery does not diminish median survivorship among patients >80 years of age.
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