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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

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Decrease in prostate cancer incidence and mortality in Germany - effects of opportunistic PSA screening or more?

V Rohde¹, W Weidner, A Katalinic

¹Department of Urology, Helios Agnes Karll Hospital, Bad Schwartau, Germany.

Urologia Internationalis

|September 16, 2009

Summary

This summary is machine-generated.

Prostate cancer incidence rose in Schleswig-Holstein due to PSA screening, with earlier diagnoses and a 20% mortality decrease. Further PSA screening effects on prostate cancer mortality remain uncertain.

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Area of Science:

Epidemiology
Oncology
Public Health

Background:

Discusses the increasing incidence and controversial interpretations of improved survival rates in prostate carcinoma epidemiology.
Highlights the need to analyze recent data from the Cancer Registry Schleswig-Holstein.

Purpose of the Study:

To analyze recent epidemiological data on prostate carcinoma in Schleswig-Holstein.
To investigate trends in incidence, diagnosis, and mortality rates between 1999 and 2005.

Main Methods:

Descriptive analysis of population-based cancer registry data.
Evaluation of data from 2.8 million inhabitants for the period 1999-2005.

Main Results:

Increased frequency of prognostically favorable diagnoses (Stage I/II) from 62.9% to 67.9%.
Age-adjusted incidence rose by 30% from 1999-2003, then declined.
Mortality decreased by 20% from 1999-2005.

Conclusions:

Assumes regular PSA testing in a subset of men influenced incidence trends.
Interprets the initial incidence rise as a screening prevalence effect, followed by a decline.
States that the long-term impact of PSA testing on prostate cancer mortality is not yet clear.