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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
Published on: July 11, 2013
Paediatric psoriasis--narrowband UVB treatment
P Zamberk1, D Velázquez, M Campos
1Dermatology Department, Hospital General Universitario Gregorio Marañón, Madrid, Spain. pamezm@hotmail.com
Journal of the European Academy of Dermatology and Venereology : JEADV
|September 17, 2009
Summary
Narrowband UV-B phototherapy effectively treats paediatric psoriasis, offering a safe alternative for children with severe cases. This treatment shows good short-term safety and achieves significant remission, despite concerns about long-term effects.
Area of Science:
- Dermatology
- Phototherapy
- Paediatric Medicine
Background:
- Narrowband UV-B is a recognized psoriasis treatment for adults.
- Its use in children is limited due to potential long-term carcinogenic risks.
- It serves as an alternative for cases resistant to topical treatments.
Purpose of the Study:
- To assess the efficacy and short-term safety of narrowband UV-B in paediatric psoriasis.
- To compare findings with existing paediatric psoriasis studies.
Main Methods:
- Narrowband UV-B was administered to 20 children with psoriasis refractory to topical therapy over 2 years and 4 months.
- Treatment response was quantified using the Psoriasis Area and Severity Index (PASI).
Main Results:
- Twenty children (median age 13) received treatment, with a median initial PASI of 8.25.
- A median of 28 sessions led to near-complete remission in most patients.
- No severe adverse events were reported; remission duration averaged 8 months.
Conclusions:
- Narrowband UV-B is an effective and well-tolerated option for paediatric psoriasis.
- Despite limited data on long-term effects, it is a viable alternative for severe paediatric cases.
- Further research is needed to address long-term safety concerns in children.
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