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Published on: February 24, 2023
Mycoplasma pneumoniae infection associated with pancytopenia: a case report
Orhan Gursel1, Demet Altun, Abdullah Avni Atay
1Department of Pediatric Hematology, Medical Faculty, Gulhane Military Medical Academy, Ankara, Turkey. orhangursel08@mynet.com
Abstract:
Immune hemolytic anemia is a rare condition in childhood. Cold agglutinins have been implicated in the etiology of the hemolysis and frequently observed during Mycoplasma pneumoniae infections. We present here a case of cold agglutinin-related hemolytic anemia, thrombocytopenia, and leukopenia secondary to M. pneumoniae associated pneumonia. It is suggested that even though very rare, M. pneumoniae infection should be considered as the underlying disease in a patient presenting with pancytopenia.
Insights
Childhood immune hemolytic anemia can be caused by Mycoplasma pneumoniae infections. This rare case highlights M. pneumoniae pneumonia leading to cold agglutinin-related pancytopenia.
Area of Science:
- Pediatrics
- Hematology
- Infectious Diseases
Background:
- Immune hemolytic anemia is a rare pediatric condition.
- Cold agglutinins are often linked to Mycoplasma pneumoniae infections.
Observation:
- A case of cold agglutinin-related hemolytic anemia, thrombocytopenia, and leukopenia is presented.
- The patient had Mycoplasma pneumoniae associated pneumonia.
Findings:
- Mycoplasma pneumoniae infection can lead to pancytopenia.
- Cold agglutinins were implicated in the observed hemolysis.
Implications:
- Mycoplasma pneumoniae should be considered in pediatric patients with pancytopenia.
- Early diagnosis and treatment of M. pneumoniae can prevent severe hematologic complications.
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