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Updated: Jun 20, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Sleep-related breathing disorders].
Harriet Akre1, Britt Øverland, Olav Skatvedt
1Øre-nese-hals-avdelingen, Lovisenberg Diakonale Sykehus, 0440 Oslo, Norway. harriet.akre@lds.no
Sleep-related breathing disorders (SRBD), including Obstructive Sleep Apnoea Syndrome (OSAS), affect 10-15% of children and adults. Early diagnosis and treatment are crucial to prevent reduced cognitive function and improve quality of life.
Area of Science:
- Sleep Medicine
- Respiratory Medicine
Context:
- Sleep-related breathing disorders (SRBD) encompass various conditions affecting sleep quality and respiratory function.
- Prevalence rates for SRBD are significant, impacting approximately 10-15% of both pediatric and adult populations.
Purpose:
- To provide a comprehensive overview of SRBD, detailing their etiology, diagnostic methods, available treatments, and the consequences of untreated disease.
- To highlight the specific characteristics and management of Obstructive Sleep Apnoea Syndrome (OSAS), the most severe form of SRBD.
Summary:
- SRBD symptoms include snoring, observed apneas, and daytime sleepiness in adults, while children may exhibit hyperactivity and learning difficulties.
- Diagnosis requires a sleep study, with continuous positive-pressure ventilation as a primary treatment for moderate to severe cases. Surgery is the preferred option for children.
- Untreated SRBD leads to increased mortality and morbidity, including reduced cognitive function and diminished quality of life in affected individuals.
Impact:
- Effective management of SRBD can mitigate serious health consequences, improving patient outcomes and overall well-being.
- Understanding the diverse manifestations and treatment options for SRBD is essential for healthcare providers to offer optimal patient care.
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