Related Experiment Video
Updated: Jun 20, 2026
09:31
Visualization of Amyloid β Deposits in the Human Brain with Matrix-assisted Laser Desorption/Ionization Imaging Mass Spectrometry
Published on: March 7, 2019
[Amyloid centers in Europe: the EURAMY project]
1Department of Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Rudbeck Laboratory, C5, 751 85 Uppsala, Sweden. per.westermark@genpat.uu.se
Der Pathologe
|September 17, 2009
Summary
Systemic amyloidoses are rare protein deposition diseases worldwide. Further research into their mechanisms and diagnostics is crucial for developing new treatments.
Area of Science:
- Protein deposition diseases
- Molecular biology
- Pathogenesis
Context:
- Systemic amyloidoses are a group of rare, globally distributed protein deposition diseases.
- Understanding the molecular mechanisms is key to addressing these serious conditions.
- Recent therapeutic advances highlight the need for continued research.
Purpose:
- To advance research on systemic amyloidoses.
- To improve diagnostic procedures.
- To explore molecular aspects and patient treatment.
Summary:
- The EURAMY program focuses on comprehensive research into systemic amyloidoses.
- Research spans from fundamental molecular mechanisms to clinical patient treatment.
- The initiative aims to foster a deeper understanding and better management of these diseases.
Impact:
- Enhanced understanding of amyloidosis pathogenesis.
- Development of improved diagnostic tools.
- Potential for novel therapeutic strategies for patients.
Related Concept Videos
03:03Amyloid Fibrils
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
03:03Amyloid Fibrils
Amyloid fibrils are aggregates of misfolded proteins. Under most circumstances, misfolded proteins are either refolded by chaperone proteins or degraded by the proteasome. However, in the case of a mutation or a disease, these proteins can accumulate to form large clusters and often further assemble to form elongated fibers, called fibrils.
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining, normally used to...