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[Retrospective case analysis of ophthalmological and systemic risk factors in patients with retinal vascular

C Klatt1, K Purtskhvanidze, H Hasselbach

  • 1Klinik für Ophthalmologie, Universitätsklinikum Schleswig-Holstein, Campus Kiel, Arnold Heller-Strasse 3, Haus 25, Kiel, Deutschland. cklatt@auge.uni-kiel.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|September 17, 2009
PubMed

Insights

Systemic hypertension is a major risk factor for central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO). Diagnostic tools like transthoracic echocardiography and carotid Doppler are crucial for identifying embolic sources in CRAO.

Area of Science:

  • Ophthalmology
  • Cardiology
  • Vascular Medicine

Context:

  • Central retinal artery occlusion (CRAO) and central retinal vein occlusion (CRVO) are serious vascular events affecting vision.
  • Identifying systemic risk factors and diagnostic tools is crucial for managing these conditions.

Purpose:

  • To determine systemic risk factors for CRAO and CRVO.
  • To evaluate the diagnostic utility of systemic investigations in CRAO and CRVO patients.

Summary:

  • Retrospective chart review of 80 patients (38 CRAO, 42 CRVO) included systemic diagnostics such as blood pressure, cholesterol, carotid Doppler, transthoracic echocardiography (TTE), and thrombophilia screening.
  • Systemic hypertension was prevalent in both CRAO (76.3%) and CRVO (75.6%) patients.
  • Abnormal cardiac findings were more frequent in CRAO (61%) than CRVO (22%), while abnormal carotid findings were also higher in CRAO (44.1%) versus CRVO (9.5%).
  • Thrombophilic factors were present in approximately 15% of patients in both groups.

Impact:

  • Transthoracic echocardiography (TTE) and carotid Doppler are valuable for diagnosing embolic sources in CRAO.
  • These tools are less frequently diagnostic for CRVO.
  • Thrombophilia screening is recommended in younger patients or those lacking common risk factors.
  • Adequate control of systemic hypertension is essential for managing CRAO and CRVO.
Abstract

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