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Enzyme immunoassay--a method of serological survey of measles vaccination
S L Vedunova1, I V Mikheeva, N N Maltseva
1Moscow Research Institute of Viral Preparations, U.S.S.R. Ministry of Health.
Acta Virologica
|February 1, 1990
Abstract:
Enzyme immunoassay (EIA) for detection of antibodies to measles virus designed in the Moscow Research Institute of Viral Preparations has proved highly sensitive (98%) and specific (100%) as tested in 492 vaccinated children. Comparison of EIA and haemagglutination inhibition (HI) test allowed to determine the cut-off value of the optical density to be equal to 0.1. The serum dilution 1:10 was found appropriate for the screening.