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Updated: Jun 20, 2026

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

Published on: November 7, 2018

Salmonella derby cross-protection study.

K J Groninga¹, E Springer, M Braunschmidt

¹Swine Health Consultant, Grand Laboratories, Inc., 1447 140th St., Larchwood, IA 51241, USA.

Veterinary Therapeutics : Research in Applied Veterinary Medicine

|September 18, 2009

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An avirulent live Salmonella choleraesuis vaccine reduced Salmonella derby reisolation rates in pigs. Further research is needed to confirm these promising findings for swine health.

Area of Science:

Veterinary immunology
Swine infectious diseases
Bacteriology

Background:

Salmonella infections pose a significant threat to swine health and food safety.
Salmonella derby is a common environmental serotype impacting pig populations.
Effective vaccination strategies are crucial for controlling Salmonella in pigs.

Purpose of the Study:

To evaluate the efficacy of an avirulent live Salmonella choleraesuis vaccine (Salmo Shield Live) against Salmonella derby challenge in pigs.
To assess the impact of vaccination timing on vaccine effectiveness.

Main Methods:

Pigs were vaccinated with an avirulent live (AVL) Salmonella choleraesuis vaccine at weaning or 3 weeks of age.
Vaccinated and unvaccinated control pigs were intranasally challenged with Salmonella derby.

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A High-throughput Platform for the Screening of Salmonella spp./Shigella spp.

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Published on: November 7, 2018

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Pigs were euthanized at 2, 4, and 6 weeks post-challenge for bacterial culture to determine reisolation rates of S. derby.

Main Results:

Vaccinated pigs exhibited significantly reduced reisolation rates of Salmonella derby compared to unvaccinated controls.
The study observed a trend towards lower bacterial shedding in vaccinated groups, though sample size was limited.
No definitive conclusions could be drawn due to the small number of pigs studied.

Conclusions:

The avirulent live Salmonella choleraesuis vaccine demonstrated potential in reducing Salmonella derby shedding in pigs.
Further comprehensive research is warranted to validate these preliminary findings and establish robust conclusions.
This vaccine may offer a viable tool for managing Salmonella infections in swine herds.