Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Chemotaxis and Direction of Cell Migration01:21

Chemotaxis and Direction of Cell Migration

Cells can detect chemical cues in their environment and reorganize the cytoskeleton to migrate toward them or away from them. This directional migration, called chemotaxis, is essential during embryogenesis and development, immune response, tissue repair and regeneration, and reproduction. These chemical cues can either attract or repel the cell's movement. For example, axon development is determined by a combination of chemoattractants and chemorepellents that direct the growing axon towards...
Inductive Effects on Chemical Shift: Overview01:27

Inductive Effects on Chemical Shift: Overview

The protons in unsubstituted alkanes are strongly shielded with chemical shifts below 1.8 ppm. Methine, methylene, and methyl protons appear at approximately 1.7, 1.2 and 0.7 ppm, while the proton signal from methane appears at 0.23 ppm. An electronegative substituent, such as chlorine, withdraws the electron density from the protons, increasing their chemical shift. Progressive substitution of the hydrogens in methane by chlorine shifts the proton signals increasingly downfield, to 3.05 ppm in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development and extensive sequencing of a broadly-consented Genome in a Bottle matched tumor-normal pair.

bioRxiv : the preprint server for biology·2024
Same author

Therapeutic management of fibrosis in systemic sclerosis patients - an analysis from the Swiss EUSTAR cohort.

Swiss medical weekly·2024
Same author

Serious infection risk of tofacitinib compared to biologics in patients with rheumatoid arthritis treated in routine clinical care.

Scientific reports·2023
Same author

[Think Interdisciplinary to Improve a Complex Multifactorial Gait Disorder of a 28-Year-Old Polio Patient].

Praxis·2023
Same author

The role of C5a-C5aR1 axis in bone pathophysiology: A mini-review.

Frontiers in cell and developmental biology·2022
Same author

Long-term persistence of antibodies after diphtheria/tetanus vaccination in immunosuppressed patients with inflammatory rheumatic diseases and healthy controls.

Vaccine·2022
Same journal

Ruliological Resilience: Pattern Restoration and Robustness in Wolfram Patterns. A Basis for Regeneration, Not Just in Cone Shells?

Bio Systems·2026
Same journal

The quantum-to-classical transducer: A thermodynamic and quantum mechanical framework for the emergence of bioenergetics.

Bio Systems·2026
Same journal

Forward-backward gene expression binarization for boolean state inference over a known regulatory network.

Bio Systems·2026
Same journal

Partial-label metric ceilings for evaluating gene regulatory networks inferred from single-cell foundation models.

Bio Systems·2026
Same journal

The impedance mismatch theory: A non-equilibrium thermodynamic framework for a shared energetic stress pathway in neurodegeneration.

Bio Systems·2026
Same journal

Immune signal-status misclassification: A theoretical framework for biological status assignment and failed status resolution.

Bio Systems·2026
See all related articles

Related Experiment Video

Updated: Jun 20, 2026

Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation
10:40

Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation

Published on: November 9, 2017

Implementation of a Hebbian chemoreceptor model for diffusive source localization.

Gail Rosen1, Paul Hasler, Mark T Smith

  • 1Electrical and Computer Engineering (ECE), Drexel University, Philadelphia, PA 19130, USA. gailr@ece.drexel.edu

Bio Systems
|September 18, 2009
PubMed
Summary
This summary is machine-generated.

This study models cellular chemical detection for improved landmine and substance localization. The new method enhances gradient source tracking using receptor clustering, outperforming existing chemotaxis algorithms.

More Related Videos

Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches
07:23

Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches

Published on: August 4, 2014

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Related Experiment Videos

Last Updated: Jun 20, 2026

Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation
10:40

Assessment of Dictyostelium discoideum Response to Acute Mechanical Stimulation

Published on: November 9, 2017

Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches
07:23

Using Insect Electroantennogram Sensors on Autonomous Robots for Olfactory Searches

Published on: August 4, 2014

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior
10:07

Generating Controlled, Dynamic Chemical Landscapes to Study Microbial Behavior

Published on: January 31, 2020

Area of Science:

  • Biomimicry
  • Chemosensation
  • Computational Biology

Background:

  • Animals are still used for landmine and substance detection due to limitations in electronic nose sensitivity and accuracy.
  • Understanding cellular chemical detection systems offers insights into biological olfaction.

Purpose of the Study:

  • To develop an enhanced method for localizing and tracking gradient sources, applicable to chemicals and heat.
  • To improve upon existing chemotaxis-inspired methods by incorporating eukaryotic receptor clustering.

Main Methods:

  • Modeling cellular chemical detection inspired by chemotaxis and Hebbian learning.
  • Implementing a eukaryotic receptor clustering model for spatio-temporal adaptation of receptors.
  • Simulating mobile and stationary sensor arrays to evaluate performance.

Main Results:

  • The receptor clustering model demonstrated improved performance over prokaryotic chemotaxis models.
  • The proposed method achieved faster convergence times in mobile simulations compared to other chemotaxis algorithms.
  • Local regions of receptor cooperation showed optimal performance, aligning with biological observations.
  • Real-time implementation with stationary sensors improved Direction-of-Arrival calculations in various environments.

Conclusions:

  • Cellular chemical detection modeling, particularly with receptor clustering, offers a promising approach for enhanced chemical and heat source localization.
  • The developed algorithm shows significant improvements in convergence time and accuracy for gradient source tracking.
  • The findings support the biological principle of receptor cooperation for optimal sensing performance.