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Updated: Jun 20, 2026

Using Brain Activation (nir-HEG/Q-EEG) and Execution Measures (CPTs) in a ADHD Assessment Protocol
Published on: April 1, 2018
Attention-deficit/hyperactivity disorder and attention networks
1Department of Psychiatry, Harvard Medical School, Boston, MA, USA. geo@nmr.mgh.harvard.edu
Investigating the neuropathophysiology of attention-deficit/hyperactivity disorder (ADHD) offers insights into normal attention and cognition. This review integrates research on ADHD neurocircuitry and its implications for understanding brain function.
Area of Science:
- Neuroscience
- Cognitive Psychology
- Psychiatry
Background:
- Attention-deficit/hyperactivity disorder (ADHD) research has advanced our understanding of cognitive functions.
- Historical models of attention have shaped neurocircuitry models of ADHD.
Purpose of the Study:
- To review the neuropathophysiology of ADHD and its bidirectional relationship with normal cognition.
- To integrate findings from ADHD research into broader neuroscience contexts.
- To explore neurocircuitry models of ADHD and their connection to attention mechanisms.
Main Methods:
- Literature review integrating historical perspectives and current research.
- Analysis of neurocircuitry models of ADHD.
- Selective review of neuroimaging data in ADHD.
Main Results:
- ADHD research illuminates normal attention, cognition, and brain function.
- Key neural systems implicated in ADHD include attention networks, reward processing, and default mode networks.
- Neuromodulatory factors play a role in these systems.
Conclusions:
- Understanding ADHD neuropathophysiology enhances knowledge of normal brain function.
- Future research should explore interactions within neural systems and neuromodulatory influences.
- Neuroimaging data provides valuable insights into both ADHD and general brain mechanisms.
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