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Assessment of Vascular Function in Patients With Chronic Kidney Disease
08:50

Assessment of Vascular Function in Patients With Chronic Kidney Disease

Published on: June 16, 2014

Zinc deficiency in chronic kidney disease: is there a relationship with adipose tissue and atherosclerosis?

Julie Calixto Lobo1, João Paulo Machado Torres, Denis Fouque

  • 1Federal University of Rio de Janeiro, Institute of Biophysics Carlos Chagas Filho, Health Science Centre, Rio de Janeiro, Brazil.

Biological Trace Element Research
|September 18, 2009
PubMed

Insights

Zinc deficiency may significantly impact atherosclerosis in chronic kidney disease (CKD) and obese patients. Further research into zinc

Area of Science:

  • Nephrology
  • Cardiology
  • Nutritional Science

Background:

  • Cardiovascular disease (CVD) is a leading cause of mortality in chronic kidney disease (CKD) patients.
  • CKD patients exhibit traditional and nontraditional risk factors for atherosclerosis, including inflammation and oxidative stress.
  • Obesity shares similarities with CKD regarding atherosclerosis and endothelial dysfunction.

Purpose of the Study:

  • To review the functions of zinc (Zn).
  • To explore the role of zinc in atherosclerosis.
  • To emphasize zinc's impact on obese patients with CKD.

Main Methods:

  • Literature review.
  • Synthesis of existing research on zinc, atherosclerosis, CKD, and obesity.

Main Results:

  • Zinc plays a crucial role in biological processes.
  • Zinc depletion is implicated in the progression of atherosclerosis.
  • The specific impact of zinc deficiency in CKD and obese populations requires further investigation.

Conclusions:

  • Zinc's role in atherosclerosis is significant, particularly in complex patient groups.
  • Understanding zinc's influence is vital for managing cardiovascular risk in CKD and obese individuals.
  • Further studies are warranted to elucidate the clinical implications of zinc status in these populations.

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