Related Experiment Video

Updated: Jun 20, 2026

A Mouse Distraction Osteogenesis Model
04:24

A Mouse Distraction Osteogenesis Model

Published on: November 14, 2018

Are endogenous BMPs necessary for bone healing during distraction osteogenesis?

Norine Alam1, René St-Arnaud, Dominique Lauzier

  • 1Division of Orthopaedics, Shriners Hospital for Children, Montréal, QC, Canada.

Clinical Orthopaedics and Related Research
|September 18, 2009
PubMed
Summary

Endogenous bone morphogenetic proteins (BMPs) are crucial for bone healing during distraction osteogenesis (DO). Genetic manipulation to reduce BMP2 in mice impaired bone formation and structural integrity, highlighting the potential of targeting endogenous BMPs for accelerated bone healing.

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