Related Experiment Video
Updated: Jun 20, 2026
08:39
Culture of Bladder Cancer Organoids as Precision Medicine Tools
Published on: December 28, 2021
[Oncology forum in urology]
Pierre Richaud1, Christophe Hennequin
1Département de Radiothérapie, Institut Bergonié, Bordeaux.
Summary
Recent prostate cancer advances highlight active surveillance for low-risk patients and refined radiotherapy strategies. Biomarkers aid treatment selection, while optimal timing for adjuvant radiotherapy and androgen deprivation duration are key considerations for improved outcomes.
Area of Science:
- Oncology
- Uro-oncology
- Radiation Oncology
Background:
- Prostate cancer incidence is rising, but mortality rates remain stable.
- Active surveillance is increasingly recommended for patients without adverse prognostic factors.
- Advances in treatment selection and management are crucial for improving patient outcomes.
Purpose of the Study:
- To summarize key advancements in prostate cancer management over the past year.
- To inform radiation oncologists about the latest developments in the field.
- To guide clinical decision-making based on recent research and congress findings.
Main Methods:
- Comprehensive review of major uro-oncology congresses (ASCO, ASTRO, AUA, EAU).
- Analysis of international scientific literature on prostate cancer.
- Synthesis of findings to present current management strategies.
Main Results:
- Increased prostate cancer incidence necessitates active surveillance for select patients.
- Biomarkers show promise in refining treatment selection.
- Adjuvant radiotherapy post-prostatectomy can reduce relapse rates, especially for pT3 R1 patients, with ongoing discussion on optimal timing.
- Combination of radiotherapy and long-term androgen deprivation improves survival in locally advanced disease, but duration must be individualized due to metabolic syndrome risks.
Conclusions:
- Significant progress has been made in prostate cancer management.
- Continued enrollment in prospective studies is vital for further therapeutic improvements.
- Personalized treatment strategies, considering patient comorbidities and risk factors, are essential.
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