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A study on the association of histological types and TNM stages
1Department of General Surgery, Liaocheng People's Hospital, 67, West Dongchang Road, Liaocheng, Shandong Province, China 252000. junxiuyu@hotmail.com
Background/Aims:
To study the association between different histological types and staging of the gastric cancer.
Methodology:
Three hundred and fifty-one patients with gastric cancer and undergone D2 or greater gastrectomy were analyzed retrospectively. The association between TNM stages and histological types, including tubular adenocarcinoma (TUB), poorly differentiated adenocarcinoma (POR), signet-ring cell carcinoma (SIG), mucinous adenocarcinoma (MUC), and undifferentiated carcinoma (UND), were analyzed by univariate and multivariate analysis.
Results:
Univariate analysis showed that the prevalence rates of T,M stages of POR, MUC, SIG, UND were not significantly different from that of TUB (all p values > 0.05). The prevalence rates of the N stage of POR, MUC, UND were significantly different from TUB p = 0.002, 0.011, 0.032). The prevalence rates of the N stage of SIG were not significantly different from TUB (p = 0.070). Multivariate analysis indicated that there was no histological type that was influencing factors on the T, M stages of gastric cancer. MUC, SIG, UND were not influencing factors on N stage, but, POR was influencing factor on the N stage (p = 0.011).
Conclusions:
There was no association between histological type and TNM stages, except the POR, which has a significant association with the N stage of gastric cancer.
