Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Overview of Regeneration and Repair01:19

Overview of Regeneration and Repair

5.8K
Regeneration and repair processes are critical in healing damages caused by injury, disease, and aging. In regeneration, the damaged tissue is entirely replaced with new growth that restores the original architecture and function. In contrast, tissue repair usually results in a fixed tissue architecture involving scar formation. Scars generally do not reestablish tissue function and may also exhibit structural abnormalities at the injury site.
Regeneration
All animals have varying degrees of...
5.8K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.8K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.8K
Tooth Anatomy01:21

Tooth Anatomy

2.7K
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

What is Missing for Stem Cell-Based Therapies in Dentistry.

The Journal of the Tennessee Dental Association·2018
Same author

The coming era of regenerative endodontics: what an endodontist needs to know.

The Alpha omegan·2011
Same author

Activin A expression regulates multipotency of mesenchymal progenitor cells.

Stem cell research & therapy·2010
Same journal

Industry updates in advanced therapy medicinal products and regenerative medicine - May 2026.

Regenerative medicine·2026
Same journal

Ethical, legal, and social issues associated with human fetal tissue research in Japan.

Regenerative medicine·2026
Same journal

The future of hematopoietic stem cell and stem cell gene therapy for metabolic diseases.

Regenerative medicine·2026
Same journal

Exploring gene therapy for developmental and epileptic encephalopathies (DEEs): possibilities or promises?

Regenerative medicine·2026
Same journal

Industry updates in advanced therapy medicinal products and regenerative medicine - April 2026.

Regenerative medicine·2026
Same journal

Optimizing strategies in tendon tissue engineering through effective scaffold design: overview of recent advancements.

Regenerative medicine·2026
See all related articles

Related Experiment Video

Updated: Mar 24, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.5K

Pulp and dentin tissue engineering and regeneration: current progress.

George T J Huang1

  • 1Columbia University, College of Dental Medicine, Section of Oral & Diagnostic Sciences, Division of Endodontics, 630 West 168th St. Ph7 E, Rm 117, New York, NY 10032, USA. gth2102@columbia.edu

Regenerative Medicine
|September 19, 2009
PubMed
Summary
This summary is machine-generated.

Dental pulp regeneration is challenging due to its enclosed nature. Modern tissue engineering and dental stem cells offer new hope for regenerating pulp and dentin tissue, advancing restorative dentistry.

More Related Videos

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

12.0K
Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

27.4K

Related Experiment Videos

Last Updated: Mar 24, 2026

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells
03:45

Author Spotlight: Advancing Tissue Regeneration and Disease Modeling with Dental Pulp Stem Cells

Published on: May 5, 2023

3.5K
Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice
07:07

Development of a Direct Pulp-capping Model for the Evaluation of Pulpal Wound Healing and Reparative Dentin Formation in Mice

Published on: January 12, 2017

12.0K
Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods
14:52

Isolation, Characterization and Comparative Differentiation of Human Dental Pulp Stem Cells Derived from Permanent Teeth by Using Two Different Methods

Published on: November 24, 2012

27.4K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Dental Research

Background:

  • Dental pulp is susceptible to infection, necessitating root-canal therapy.
  • Pulp regeneration is difficult due to the dentin encasement and limited blood supply.
  • Traditional root-canal therapy involves pulp removal and filling, not regeneration.

Purpose of the Study:

  • To review historical attempts at dental pulp regeneration.
  • To discuss current advancements in pulp and dentin tissue engineering.
  • To explore the future potential of regenerative approaches in dentistry.

Main Methods:

  • Literature review of early pulp regeneration studies.
  • Analysis of current tissue engineering strategies for pulp and dentin.
  • Discussion of emerging technologies and stem cell applications.

Main Results:

  • Early regeneration attempts faced significant limitations.
  • Modern tissue engineering shows promise for regenerating pulp and dentin.
  • Dental stem cells are key to current regenerative efforts.

Conclusions:

  • Regenerative endodontics is a rapidly advancing field.
  • Tissue engineering offers a viable alternative to conventional root-canal therapy.
  • Future research focuses on enhancing vascularization and functional pulp recovery.