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Related Concept Videos

Arteries of Lower Limbs01:20

Arteries of Lower Limbs

The external iliac artery transitions out of the body cavity, entering the femoral region of the lower leg, and is renamed the femoral artery at the point where it traverses the body wall. This artery is responsible for the distribution of blood to the thigh's deep muscles and the skin's ventral and lateral regions, achieved through several minor branches and the lateral deep femoral artery, which also spawns a lateral circumflex artery. The knee area receives blood from the genicular artery,...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Arteries of the Upper Limbs01:12

Arteries of the Upper Limbs

The subclavian artery transitions into the axillary artery as it exits the chest and enters the axillary region. This artery is critical for supplying blood to the shoulder area, including the head of the humerus, through the humeral circumflex arteries. As the vessel continues into the upper arm or brachium, it becomes the brachial artery. This artery plays a key role in vascularizing the brachial region and bifurcates at the elbow into several branches. These branches include the deep...
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies01:22

Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies

The key clinical manifestations of Rheumatic heart disease (RHD) include several distinct cardiac symptoms.Carditis, a hallmark of acute rheumatic fever, involves inflammation of the heart's endocardium, myocardium, and pericardium. Chronic RHD often results from recurrent episodes of carditis. Its symptoms include the following:Murmurs are caused by valvular damage, especially to the mitral and aortic valves. Mitral stenosis or regurgitation is common, with characteristic heart murmurs...
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

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Related Experiment Video

Updated: Jun 20, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

[Limb arteritis in Horton disease: five cases].

L Benjilali1, Z Tazi Mezalek, J Raffali

  • 1Service de médecine interne, hôpital Ibn Sina, Rabat, Maroc.

La Revue De Medecine Interne
|September 19, 2009
PubMed
Summary

Giant cell arteritis can affect limbs, often presenting as the initial symptom. This condition may mimic arteriosclerosis, necessitating early diagnosis and treatment to prevent severe outcomes like amputation.

More Related Videos

Methods for Acute and Subacute Murine Hindlimb Ischemia
07:57

Methods for Acute and Subacute Murine Hindlimb Ischemia

Published on: June 21, 2016

Related Experiment Videos

Last Updated: Jun 20, 2026

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model
08:16

High-Resolution Three-Dimensional Imaging of the Footpad Vasculature in a Murine Hindlimb Gangrene Model

Published on: March 16, 2022

Methods for Acute and Subacute Murine Hindlimb Ischemia
07:57

Methods for Acute and Subacute Murine Hindlimb Ischemia

Published on: June 21, 2016

Area of Science:

  • Vascular Medicine
  • Rheumatology
  • Arteritis

Context:

  • Giant cell arteritis (GCA) is a systemic vasculitis typically affecting large and medium-sized arteries.
  • Limb involvement in GCA is infrequently reported and often asymptomatic, leading to potential underdiagnosis.

Purpose:

  • To describe the distinct characteristics of limb involvement in patients with giant cell arteritis.
  • To highlight limb arteritis as a potential presenting feature of GCA.

Summary:

  • A retrospective study identified 5 out of 50 (10%) GCA patients with symptomatic limb arteriopathy.
  • Limb arteritis was the primary manifestation in 4 patients, presenting with arteriographic findings of occlusion or moniliform stenosis.
  • Despite treatment, 4 patients required amputations due to ischemic complications.

Impact:

  • Recognizing limb arteritis as a potential GCA manifestation is crucial for timely diagnosis.
  • This can help differentiate GCA from arteriosclerosis, a common condition in the elderly.
  • Early intervention may prevent severe ischemic complications and limb loss.