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Related Experiment Video

Updated: Jun 20, 2026

Behavioral Determination of Stimulus Pair Discrimination of Auditory Acoustic and Electrical Stimuli Using a Classical Conditioning and Heart-rate Approach
10:50

Behavioral Determination of Stimulus Pair Discrimination of Auditory Acoustic and Electrical Stimuli Using a Classical Conditioning and Heart-rate Approach

Published on: June 6, 2012

Auditory midbrain implant: a review.

Hubert H Lim1, Minoo Lenarz, Thomas Lenarz

  • 1Department of Biomedical Engineering, University of Minnesota, Minneapolis. hlim@umn.edu

Trends in Amplification
|September 19, 2009
PubMed
Summary
This summary is machine-generated.

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The auditory midbrain implant (AMI) offers hearing improvements for deaf patients. Current results show promise, but open-set speech perception remains a challenge, requiring further research.

Area of Science:

  • Neuroscience
  • Biomedical Engineering
  • Otolaryngology

Background:

  • Cochlear implants are insufficient for some profoundly deaf patients.
  • The auditory midbrain implant (AMI) targets the inferior colliculus for auditory stimulation.
  • Previous research and animal studies paved the way for clinical translation.

Purpose of the Study:

  • To review the development and research leading to the first clinical applications of the AMI.
  • To present the rationale, design, and preclinical data supporting the AMI.
  • To summarize initial surgical, psychophysical, and speech outcomes in the first three AMI patients.

Main Methods:

  • Review of developmental research and preclinical safety/feasibility studies.
  • Surgical implantation of a 20-electrode single-shank AMI array.

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Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
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Published on: January 9, 2019

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Last Updated: Jun 20, 2026

Behavioral Determination of Stimulus Pair Discrimination of Auditory Acoustic and Electrical Stimuli Using a Classical Conditioning and Heart-rate Approach
10:50

Behavioral Determination of Stimulus Pair Discrimination of Auditory Acoustic and Electrical Stimuli Using a Classical Conditioning and Heart-rate Approach

Published on: June 6, 2012

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice
09:06

Cochlear Implant Surgery and Electrically-evoked Auditory Brainstem Response Recordings in C57BL/6 Mice

Published on: January 9, 2019

  • Assessment of psychophysical and speech perception abilities in implanted patients.

    • Main Results:

    • Encouraging safety and functionality of the AMI observed in early trials.
    • All implanted patients demonstrated daily hearing improvements.
    • Significant variability in patient performance linked to implant location; open-set speech perception not yet achieved without lip-reading.

    Conclusions:

    • The AMI shows potential for hearing restoration in specific deaf populations.
    • Current stimulation strategies may not adequately integrate auditory cues for open-set speech understanding.
    • Further research is needed to optimize AMI placement, stimulation, and electrode design for improved speech perception.