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Updated: Jun 20, 2026

Probing Structural and Dynamic Properties of Trafficking Subcellular Nanostructures by Spatiotemporal Fluctuation Spectroscopy
Published on: August 16, 2021
Comment on "The dynamic control of kiss-and-run and vesicular reuse probed with single nanoparticles"
Björn Granseth1, Benjamin Odermatt, Stephen J Royle
1Department of Clinical and Experimental Medicine, Division of Cell Biology, Linköping University, SE 581 83 Linköping, Sweden.
Abstract:
Zhang et al. (Research Articles, 13 March 2009, p. 1448) reported that synaptic vesicles usually release neurotransmitter through a kiss-and-run mechanism occurring within 1 second but that full collapse of the vesicles becomes more prevalent with repeated stimuli. We report that the kinetics of vesicle retrieval do not change during a stimulus train, with endocytosis occurring in 10 to 15 seconds.
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