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Updated: Jun 20, 2026

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A Novel Technique for Generating and Observing Chemiluminescence in a Biological Setting
Published on: March 9, 2017
Iridium doped silica-PEG nanoparticles: enabling electrochemiluminescence of neutral complexes in aqueous media
Simone Zanarini1, Enrico Rampazzo, Sara Bonacchi
1Dipartimento di Chimica G. Ciamician, Universita di Bologna, Via Selmi 2, 40126 Bologna, Italy. simone.zanarini@unibo.it
Journal of the American Chemical Society
|September 22, 2009
Abstract:
We report for the first time the stable electrochemiluminescence of a completely insoluble neutral Ir(III) complex in aqueous media. The strategy adopted is the encapsulation of emitting dye into silica-PEG nanoparticles. This nanoassembly by limiting water and oxygen quenching and allowing solubilization makes the electrogeneration of the excited state feasible under typical bioassay conditions.

