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Updated: Jun 20, 2026
07:35
Evaluation of Colorectal Cancer Risk and Prevalence by Stool DNA Integrity Detection
Published on: June 8, 2020
Advances in colorectal cancer screening
1Cleveland Clinic Foundation, Digestive Disease Institute, Department of Gastroenterology and Hepatology, Cleveland, OH 44195, USA.
Current Gastroenterology Reports
|September 22, 2009
Summary
Colorectal cancer screening is crucial, yet underutilized. This review assesses various screening methods, including new fecal and imaging tests, to improve detection rates in diverse populations.
Area of Science:
- Oncology
- Gastroenterology
- Preventive Medicine
Background:
- Colorectal cancer (CRC) is a leading cause of cancer death in the US.
- Screening has reduced CRC incidence and mortality, but uptake remains suboptimal.
- An aging and diverse population requires diverse screening options.
Purpose of the Study:
- To assess the effectiveness and limitations of available colorectal cancer screening modalities.
- To review new screening tests recommended by updated guidelines.
- To evaluate advancements in existing colorectal cancer screening methods.
Main Methods:
- Review of current literature on colorectal cancer screening.
- Assessment of established screening tests: guaiac-based fecal occult blood tests and colonoscopy.
- Evaluation of newer screening modalities: fecal immunochemical tests, fecal DNA, and CT colonography.
Main Results:
- Only about half of eligible individuals undergo CRC screening.
- Newer screening modalities offer alternatives to traditional methods.
- Advances in existing tests aim to improve accuracy and patient acceptance.
Conclusions:
- A variety of CRC screening methods are necessary to meet population demands.
- Updated guidelines endorse new fecal and imaging-based tests.
- Continued evaluation of screening effectiveness is vital for CRC prevention.
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