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Light-mediated Reversible Modulation of the Mitogen-activated Protein Kinase Pathway during Cell Differentiation and Xenopus Embryonic Development
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Light-mediated remote control of signaling pathways.

Melanie A Priestman1, David S Lawrence

  • 1Department of Chemistry, The University of North Carolina at Chapel Hill, Kenan Laboratories, Campus Box 3290, Chapel Hill, NC 27599-3290, USA.

Biochimica Et Biophysica Acta
|September 22, 2009
PubMed
Summary

Researchers developed novel light-activated intracellular probes to precisely control cell signaling. These tools revealed protein kinase C beta (PKCbeta) is crucial for cell division and cofilin

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