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Updated: Jun 20, 2026

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Controlled Cortical Impact Model for Traumatic Brain Injury
Published on: August 5, 2014
Identifying survivors with traumatic craniocervical dissociation: a retrospective study
Zara Cooper1, Joel A Gross, J Matthew Lacey
1Department of Surgery, Brigham and Women's Medical Center, Harvard University, Boston, Massachusetts 02115, USA. zcooper@partners.org
The Journal of Surgical Research
|September 22, 2009
Summary
Survivors of traumatic craniocervical dissociation (CCD) had higher Glasgow Coma Scale (GCS) scores and were more likely to be normotensive. A wider basion-dental interval (BDI) was associated with mortality in these severe injuries.
Area of Science:
- Trauma Surgery
- Neurosurgery
- Emergency Medicine
Background:
- Traumatic craniocervical dissociation (CCD) is a severe injury often fatal at the scene.
- Increasingly, patients with CCD are surviving to reach medical facilities.
- Identifying predictors of survival is crucial for patient management.
Purpose of the Study:
- To identify clinical and radiographic factors differentiating survivors from non-survivors of CCD.
- To understand the presentation of patients with CCD who survive.
Main Methods:
- Retrospective review of trauma registry and medical examiner databases (2001-2006).
- Inclusion of patients aged 12+ diagnosed with CCD via ICD-9, X-ray, or CT.
- Analysis of demographics, injury mechanism, clinical presentation, interventions, and radiographic findings.
Main Results:
- Seven out of 69 CCD patients survived to discharge.
- Survivors had significantly higher Glasgow Coma Scale (GCS) scores and were more often normotensive.
- Non-survivors were more likely to have a basion-dental interval (BDI) greater than or equal to 16mm and cervical cord injury.
Conclusions:
- Trauma patients with CCD, cervical cord injury, requiring CPR, and GCS of 3 have a grim prognosis.
- A wider basion-dental interval (BDI) is a significant predictor of mortality in craniocervical dissociation injuries.
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