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Related Concept Videos

Neurulation01:30

Neurulation

Neurulation is the embryological process which forms the precursors of the central nervous system and occurs after gastrulation has established the three primary cell layers of the embryo: ectoderm, mesoderm, and endoderm. In humans, the majority of this system is formed via primary neurulation, in which the central portion of the ectoderm—originally appearing as a flat sheet of cells—folds upwards and inwards, sealing off to form a hollow neural tube. As development proceeds, the anterior...
Peritoneum01:21

Peritoneum

The peritoneum is a vital membrane that lines the abdominal cavity and covers most of the organs within it. It plays a crucial role in protecting the organs, providing a smooth surface for their movement, and facilitating various physiological processes. Understanding the anatomy and function of the peritoneum is essential for comprehending the complexities of the abdominal region.
Anatomy of the Peritoneum
The peritoneum is divided into two layers: the parietal peritoneum and the visceral...
Nerve Supply of the GI Tract01:27

Nerve Supply of the GI Tract

The neuronal supply to the gastrointestinal (GI) tract is essential for regulating various functions, including digestion, absorption, and movement of food. This intricate network of nerves is known as the enteric nervous system (ENS), often referred to as the "second brain" of the body.
The enteric nervous system consists of two major plexuses: the myenteric plexus (Auerbach's plexus) and the submucosal plexus (Meissner's plexus). These plexuses are located within the layers of the GI tract...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Spinal Nerves: Plexus I01:22

Spinal Nerves: Plexus I

Nerve plexuses are networks of interlacing nerves that serve as communication hubs to distribute and organize nerve action across various body regions. The nerve plexuses are organized into the cervical plexus located in the neck region, brachial plexus in the shoulder area, lumbar plexus found in the lower back, sacral plexus situated in the pelvis, and coccygeal plexus located in the coccygeal region.
The Cervical Plexus
The cervical plexus, formed by the anterior rami of the first four...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...

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Related Experiment Video

Updated: Jun 20, 2026

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
09:55

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion

Published on: April 23, 2018

Intraneural perineurioma.

H-Y Lee1, R G Manasseh, R H Edis

  • 1Department of Anatomical Pathology, Section of Neuropathology, Royal Perth Hospital, 2nd Floor North Block, Wellington Street Campus, Perth, Western Australia 6847, Australia.

Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia
|September 22, 2009
PubMed
Summary
This summary is machine-generated.

Intraneural perineurioma, a rare nerve tumor, can mimic hereditary neuropathies. Accurate diagnosis requires detailed neuropathology to differentiate these conditions.

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Last Updated: Jun 20, 2026

An In Vivo Murine Sciatic Nerve Model of Perineural Invasion
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A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma
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A Model for Perineural Invasion in Head and Neck Squamous Cell Carcinoma

Published on: January 5, 2017

Area of Science:

  • Neuropathology
  • Oncology
  • Peripheral Nerve Disorders

Background:

  • Intraneural perineurioma is a rare tumor affecting peripheral nerves.
  • Histological features can lead to confusion with hereditary motor and sensory neuropathies.

Observation:

  • Presents two cases of intraneural perineurioma.
  • Case 1: Longest reported follow-up (14 years) showing lesion extension.
  • Case 2: An 11-year-old female highlighting management controversies.

Findings:

  • Detailed neuropathology, including immunoperoxidase stains and electron microscopy, is crucial for diagnosis.
  • Thorough macroscopic and microscopic assessment by pathologists is essential.
  • The status of surgical resection margins is important in management.

Implications:

  • Highlights the importance of accurate diagnostic methods for rare nerve tumors.
  • Informs management strategies for intraneural perineurioma, considering diagnostic challenges.
  • Contributes to understanding the long-term behavior and pathological assessment of these lesions.